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Useful cardiovascular research and for the study of lipid transport. Also useful in the study of LDL metabolism and its relation to cardiovascular diseases.Lipoprotein, low density, human plasma is a large protein complex that binds cell surface receptors in vertebrates and delivers cholesterol by receptor-mediated endocytosis. Further, it is evaluated for receptor binding to human skin fibroblasts. In addition to this, it is used as a cell markers and disease marker.
Tsai, M. Y.; Steffen, B. T.; Guan, W.; McClelland, R. L.; Warnick, R.; McConnell, J.; Hoefner, D. M.; Remaley, A. T. New automated assay of small dense low-density lipoprotein cholesterol identifies risk of coronary heart disease: the Multi-ethnic Study of Atherosclerosis. Arterioscler Thromb Vasc Biol 2014, 34 (1), 196-201.
Hou, X.; Zhang, T.; Cao, A. Preparation of new amphiphilic macroporous nonwoven polymeric adsorbents aimed for selective removal of low-density lipoprotein from plasma. J. Biomed. Mater. Res. Part B Appl. Biomater. 2015, 103 (1), 52-61.
Wijers, M.; Kuivenhoven, J. A.; van de Sluis, B. The life cycle of the low-density lipoprotein receptor: insights from cellular and in-vivo studies. Curr. Opin. Lipidol. 2015, 26 (2), 82-87.