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2883-98-9 - alpha-Asarone - trans-1,2,4-Trimethoxy-5-(1-propenyl)benzene - J65125 - Alfa Aesar

J65125 alpha-Asarone

CAS Number
2883-98-9
Synonyms
trans-1,2,4-Trimethoxy-5-(1-propenyl)benzene

Size Price ($) Quantity Availability
1g 43.60
5g 129.00
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alpha-Asarone

MDL
MFCD00064457
EINECS
220-743-6

Chemical Properties

Formula
C12H16O3
Formula Weight
208.25
Form
Powder
Melting point
57-61°
Boiling Point
296°
Sensitivity
Light Sensitive
Solubility
Soluble in chloroform, methanol.

Applications

α-Asarone was used in the synthesis of series of α-asarone isomers and were investigated for their hypolipidemic and antiplatelet activities. It is used in the synthesis of anti-inflammatory neolignan. Also used in lignan syntheses for antiallergic agents. It is clinically used as medication for treating epilepsy, cough, bronchitis and asthma. It exhibits neuroprotective, anti-oxidative, anticonvulsive and cognitive enhancing action.

Notes

Store in cool, dry place in a tightly sealed container. Store away from oxidizing agents, heat. Store in refrigerator.

Literature References

J Poplawski; B Lozowicka; A T Dubis; B Lachowska; S Witkowski; D Siluk; J Petrusewicz; R Kaliszan; J Cybulski; M Strzałkowska; Z Chilmonczyk. Synthesis and hypolipidemic and antiplatelet activities of alpha-asarone isomers in humans (in vitro), mice (in vivo), and rats (in vivo). Journal of Medicinal Chemistry. 2000, 43, (20), 3671-3676.

Ze-Jun Wang; Simon R Levinson; Liqin Sun; Thomas Heinbockel. Identification of both GABAA receptors and voltage-activated Na(+) channels as molecular targets of anticonvulsant α-asarone. Frontiers in Pharmacology. 2014, 5, 40.

GHS Hazard and Precautionary Statements

Hazard Statements: H302

Harmful if swallowed.

Precautionary Statements: P264-P270-P301+P312a-P330-P501a

Wash thoroughly after handling. Do not eat, drink or smoke when using this product. IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,824
Beilstein
1910606
Harmonized Tariff Code
2909.30
TSCA
No
RTECS
DC2975000

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