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J65125 alpha-Asarone

CAS Number
2883-98-9
Synonyms
trans-1,2,4-Trimethoxy-5-(1-propenyl)benzene

Stock No. Size Price ($) Quantity Availability
J65125-03 1g 45.00
J65125-06 5g 133.00
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alpha-Asarone

MDL
MFCD00064457
EINECS
220-743-6

Chemical Properties

Formula
C12H16O3
Formula Weight
208.25
Form
Powder
Melting point
57-61°
Boiling Point
296°
Storage & Sensitivity
Light Sensitive. Ambient temperatures.
Solubility
Soluble in chloroform, methanol.

Applications

α-Asarone was used in the synthesis of series of α-asarone isomers and were investigated for their hypolipidemic and antiplatelet activities. It is used in the synthesis of anti-inflammatory neolignan. Also used in lignan syntheses for antiallergic agents. It is clinically used as medication for treating epilepsy, cough, bronchitis and asthma. It exhibits neuroprotective, anti-oxidative, anticonvulsive and cognitive enhancing action.

Notes

Store in cool, dry place in a tightly sealed container. Store away from oxidizing agents, heat. Store in refrigerator.

Literature References

J Poplawski; B Lozowicka; A T Dubis; B Lachowska; S Witkowski; D Siluk; J Petrusewicz; R Kaliszan; J Cybulski; M Strzałkowska; Z Chilmonczyk. Synthesis and hypolipidemic and antiplatelet activities of alpha-asarone isomers in humans (in vitro), mice (in vivo), and rats (in vivo). Journal of Medicinal Chemistry. 2000, 43, (20), 3671-3676.

Ze-Jun Wang; Simon R Levinson; Liqin Sun; Thomas Heinbockel. Identification of both GABAA receptors and voltage-activated Na(+) channels as molecular targets of anticonvulsant α-asarone. Frontiers in Pharmacology. 2014, 5, 40.

GHS Hazard and Precautionary Statements

Hazard Statements: H302

Harmful if swallowed.

Precautionary Statements: P264b-P270-P301+P312-P330-P501c

Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. Rinse mouth. Dispose of contents/ container to an approved waste disposal plant

Other References

Merck
14,824
Beilstein
1910606
Harmonized Tariff Code
2909.30
TSCA
No
RTECS
DC2975000

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