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303-98-0 - Coenzyme Q-10, 98+% - Ubiquinone-10 - Q-10 - J65137 - Alfa Aesar

J65137 Coenzyme Q-10, 98+%

CAS Number
303-98-0
Synonyms
Ubiquinone-10
Q-10

Size Price ($) Quantity Availability
1g 64.27
5g 128.75
25g 499.00
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Coenzyme Q-10, 98+%

MDL
MFCD00042919
EINECS
206-147-9

Chemical Properties

Formula
C59H90O4
Formula Weight
863.36
Form
Powder
Melting point
48-52°
Sensitivity
Light Sensitive
Solubility
Soluble in chloroform.

Applications

It is used as a component of electron transport chain and in aerobic cellular respiration, Coenzyme Q10 can protect human endothelial cells from oxidative damage by modulating the nitric oxide pathway. In addition, Coenzyme Q10 inhibits LDL oxidation, a major process in the development of atherosclerosis. Coenzyme Q10 is known to suppress the down regulation of NOS and up-regulation of NOS2. As a result of its ability to bind Ca2+, Coenzyme Q10 can transport this cation across artificial biomimetic membranes.

Notes

Light Sensitive. Keep container tightly closed. Store in cool, dry conditions in well sealed containers.

Literature References

Thomas Muller.; Thomas Buttner.; Ali-Farshad Gholipour.; Wilfried Kuhn. Coenzyme Q10 supplementation provides mild symptomatic benefit in patients with Parkinson's disease. Neuroscience Letters. 2003, 341, (3), 201-204.

Kommuru, T.R.; Gurley, B.; Khan, M.A.; Reddy, I.K. Self-emulsifying drug delivery systems (SEDDS) of coenzyme Q10: formulation development and bioavailability assessment. International Journal of Pharmaceutics. 2001, 212, (2), 233-246.

Other References

Merck
14,9843
Beilstein
1900141
Harmonized Tariff Code
2914.69
TSCA
Yes
RTECS
DK3900000

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