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J65261 Lipoprotein, low density, oxidized, human plasma, Hi-TBAR, 99%, BT-910X

CAS Number
Synonyms
Hi-TBar-Ox-LDL
Oxidized LDL

Stock No. Size Price ($) Quantity Availability
J65261-8+ 2mg 231.00
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Lipoprotein, low density, oxidized, human plasma, Hi-TBAR, 99%, BT-910X

MDL
MFCD00131524

Chemical Properties

Form
Liquid
Storage & Sensitivity
Keep Cold.

Applications

Oxidized LDL induces foam cell formation in some macrophage cell lines. Research on foam cell formation is relevant to the study of atherosclerosis. Cellular exposure to ox-LDL results is the formation of lipid droplets containing cholesteryl esters in the cytoplasm of the macrophage as the lipoprotein particles are metabolized by the cell.Lipoprotein, low density, oxidized, human plasma, is used to induce foam cell formation in macrophages.

Notes

TBARS: greater than equal to 45nmoles MDA/mg. Supplied at 1mg/ml in 1X phosphate-buffered saline, pH 7.4 and 0.3 mM EDTA. Aseptically packaged and sterile filtered. Store at 4°C. Do not freeze. Short shelf life: up to 6 weeks.

Literature References

Amézaga, N.;, Sanjurjo, L.; Julve, J.; Aran, G.; Pérez-Cabezas, B.; Bastos-Amador, P.; Armengol, C.; Vilella, R.; Escolà-Gil, J. C.; Blanco-Vaca, F.; Borràs, F. E.; Valledor, A. F.; Sarrias, M. R. Human scavenger protein AIM increases foam cell formation and CD36-mediated oxLDL uptakeJ Leukoc Biol 2014, 95 (3), 509-520.

Haller, E.; Lindner, W.; Lämmerhofer, M. Gold nanoparticle-antibody conjugates for specific extraction and subsequent analysis by liquid chromatography-tandem mass spectrometry of malondialdehyde-modified low density lipoprotein as biomarker for cardiovascular risk. Anal. Chim. Acta 2015, 857, 53-63.

Zhong, Q.; Zhao, S.; Yu, B.; Wang, X.; Matyal, R.; Li, Y.; Jiang, Z. High-density Lipoprotein Increases the Uptake of Oxidized Low Density Lipoprotein via PPARgamma/CD36 Pathway in Inflammatory Adipocytes. Int. J. Biol. Sci. 2015, 11 (3), 256-265.

Other References

Harmonized Tariff Code
3002.19
TSCA
No

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