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72003-83-9 - 2'-Deoxyadenosine-5'-diphosphate trisodium salt, 98% - dADP - J65307 - Alfa Aesar

J65307 2'-Deoxyadenosine-5'-diphosphate trisodium salt, 98%

CAS Number
72003-83-9
Synonyms
dADP

Size Price ($) Quantity Availability
25mg 154.50
100mg 405.20
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2'-Deoxyadenosine-5'-diphosphate trisodium salt, 98%

MDL
MFCD00083610
EINECS
276-280-5

Chemical Properties

Formula
C10H12N5Na3O9P2
Formula Weight
477.15
Form
Powder
Solubility
Soluble in water.

Applications

2?-Deoxyadenosine 5?-diphosphate is used for the synthesis of deoxyadenylate oligonucleotides with enzymes such as polynucleotide phosphorylase from Escherichia coli. dADP is used as an inhibitor of bacterial poly(A) polymerase. DeoxyADP may be use as an alternative substrate or inhibitor for studies of ATPase and DNA and RNA polymerase specificity.

Notes

Store away from strong oxidizing agents. Keep container tightly closed. Store in cool, dry conditions in well sealed containers.

Literature References

Qi Sun.; Shanshan Gong.; Jian Sun.; Si Liu.; Qiang Xiao.; Shouzhi Pu. A P(V)-N Activation Strategy for the Synthesis of Nucleoside Polyphosphates. J. Org. Chem. 2013, 78, (17), 8417-8426.

GHS Hazard and Precautionary Statements

Hazard Statements: H302-H315-H319-H335

Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280-P305+P351+P338-P304+P340-P362-P301+P312-P312-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Harmonized Tariff Code
2933.59
TSCA
No

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