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J65326 3'-Amino-2',3'-dideoxyguanosine, 99%

CAS Number
66323-49-7
Synonyms
9-(3-Amino-2,3-dideoxy-beta-D-ribofuranosyl)guanine

Stock No. Size Price ($) Quantity Availability
J65326-03 1g 153.00
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3'-Amino-2',3'-dideoxyguanosine, 99%

MDL
MFCD09750824

Chemical Properties

Formula
C10H14N6O3
Formula Weight
266.26
Form
Powder
Storage & Sensitivity
Keep Cold.
Solubility
Soluble in water (50 mg/ml).

Applications

3'-Amino-2',3'-dideoxyguanosineis used as a pharmaceutical intermediate.

Notes

Store in cool, dry place in a tightly sealed container. Store away from oxidizing agents, heat. Store in refrigerator.

Literature References

Heinz Hartmann; Markus W. Vogt; Amy G. Durno; Martin S. Hirsch; Gerhard Hunsmann; and Fritz Eckstein. Enhanced In Vitro Inhibition of HIV-1 Replication by 3?-Fluoro-3?-deoxythymidine Compared to Several Other Nucleoside Analogs. Bioorganic & Medicinal Chemistry Letters. 1988, 4, (6), 457-466.

Ralf Eisenhuth and Clemens Richert. Convenient Syntheses of 3?-Amino-2?,3?-dideoxynucleosides, Their 5?-Monophosphates, and 3?-Aminoterminal Oligodeoxynucleotide Primers. J. Org. Chem. 2009, 74, (1), 26-37.

GHS Hazard and Precautionary Statements

Hazard Statements: H302-H315-H319-H335

Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P337+P313-P362-P501c

Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Rinse mouth. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Harmonized Tariff Code
2934.99
TSCA
No

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