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3'-Amino-2',3'-dideoxyguanosineis used as a pharmaceutical intermediate.
Heinz Hartmann; Markus W. Vogt; Amy G. Durno; Martin S. Hirsch; Gerhard Hunsmann; and Fritz Eckstein. Enhanced In Vitro Inhibition of HIV-1 Replication by 3?-Fluoro-3?-deoxythymidine Compared to Several Other Nucleoside Analogs. Bioorganic & Medicinal Chemistry Letters. 1988, 4, (6), 457-466.
Ralf Eisenhuth and Clemens Richert. Convenient Syntheses of 3?-Amino-2?,3?-dideoxynucleosides, Their 5?-Monophosphates, and 3?-Aminoterminal Oligodeoxynucleotide Primers. J. Org. Chem. 2009, 74, (1), 26-37.
Hazard Statements: H302-H315-H319-H335
Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.