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14930-96-2 - Cytochalasin B - Phomin - J65342 - Alfa Aesar

J65342 Cytochalasin B

CAS Number
14930-96-2
Synonyms
Phomin

Size Price ($) Quantity Availability
5mg 210.00
10mg 308.00
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Cytochalasin B

MDL
MFCD00077704
EINECS
239-000-2

Chemical Properties

Formula
C29H37NO5
Formula Weight
479.61
Form
Powder
Melting point
218-221°
Solubility
Freely soluble in DMF, DMSO or ethanol at room temperature

Applications

Cytochalasin B is used for characterizing some of the polymerization properties of actin, and in studies on cytokinesis. Probe for the two hexose-transport systems in rat L6 myoblasts. And induces DNA fragmentation, inhibits cell division, and disrupts many cell processes. Inhibits glucose transport.

Notes

Store away from strong oxidizing agents. Keep container tightly closed. Store in cool, dry conditions in well sealed containers.

Literature References

Susan MacLean-Fletcher.; Thomas D. Pollard. Mechanism of action of cytochalasin B on actin. Cell. 1998 , 20, (2), 329-341.

Michael Fenech.; Alexander A. Morley. Measurement of micronuclei in lymphocytes. Mutation Research/Environmental Mutagenesis and Related Subjects. 1985, 147, (1-2), 29-36.

GHS Hazard and Precautionary Statements

Hazard Statements: H300-H310-H330-H361

Fatal if swallowed. Fatal in contact with skin. Fatal if inhaled. Suspected of damaging fertility or the unborn child.

Precautionary Statements: P260-P284-P301+P310-P304+P340-P320-P330-P361-P302+P350-P405-P501a

Do not breathe dust/fume/gas/mist/vapours/spray. Wear respiratory protection. IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Specific treatment is urgent (see label). Rinse mouth. Remove/Take off immediately all contaminated clothing. IF ON SKIN: Gently wash with plenty of soap and water. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,2790
Beilstein
1096207
Hazard Class
6.1
Packing Group
II
Harmonized Tariff Code
2934.99
TSCA
No
RTECS
RO0205000

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