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Cytochalasin B is used for characterizing some of the polymerization properties of actin, and in studies on cytokinesis. Probe for the two hexose-transport systems in rat L6 myoblasts. And induces DNA fragmentation, inhibits cell division, and disrupts many cell processes. Inhibits glucose transport.
Susan MacLean-Fletcher.; Thomas D. Pollard. Mechanism of action of cytochalasin B on actin. Cell. 1998 , 20, (2), 329-341.
Michael Fenech.; Alexander A. Morley. Measurement of micronuclei in lymphocytes. Mutation Research/Environmental Mutagenesis and Related Subjects. 1985, 147, (1-2), 29-36.
Hazard Statements: H300-H310-H330-H361
Fatal if swallowed. Fatal in contact with skin. Fatal if inhaled. Suspected of damaging fertility or the unborn child.
Precautionary Statements: P301+P310a-P304+P340-P320-P330-P405-P501a
IF SWALLOWED: IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Specific treatment is urgent (see label). Rinse mouth. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.