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J65342 Cytochalasin B

CAS Number
14930-96-2
Synonyms
Phomin

Stock No. Size Price ($) Quantity Availability
J65342-#0 5mg 196.00
J65342-MA 10mg 322.00
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Cytochalasin B

MDL
MFCD00077704
EINECS
239-000-2

Chemical Properties

Formula
C29H37NO5
Formula Weight
479.61
Form
Powder
Melting point
218-221°
Storage & Sensitivity
Store at -20°C.
Solubility
Freely soluble in DMF, DMSO or ethanol at room temperature

Applications

Cytochalasin B is used for characterizing some of the polymerization properties of actin, and in studies on cytokinesis. Probe for the two hexose-transport systems in rat L6 myoblasts. And induces DNA fragmentation, inhibits cell division, and disrupts many cell processes. Inhibits glucose transport.

Notes

Store away from strong oxidizing agents. Keep container tightly closed. Store in cool, dry conditions in well sealed containers.

Literature References

Susan MacLean-Fletcher.; Thomas D. Pollard. Mechanism of action of cytochalasin B on actin. Cell. 1998 , 20, (2), 329-341.

Michael Fenech.; Alexander A. Morley. Measurement of micronuclei in lymphocytes. Mutation Research/Environmental Mutagenesis and Related Subjects. 1985, 147, (1-2), 29-36.

GHS Hazard and Precautionary Statements

Hazard Statements: H300+H310+H330-H361

Fatal if swallowed. Fatal in contact with skin. Fatal if inhaled. Suspected of damaging fertility or the unborn child.

Precautionary Statements: P201-P202-P260-P262-P264b-P270-P271-P281-P284-P301+P310-P302+P350-P304+P340-P308+P313-P310-P330-P361-P363-P501c

Obtain special instructions before use. Do not handle until all safety precautions have been read and understood. Do not breathe dust/fume/gas/mist/vapours/spray. Do not get in eyes, on skin, or on clothing. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Use only outdoors or in a well-ventilated area. Use personal protective equipment as required. Wear respiratory protection. IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. IF ON SKIN: Gently wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF exposed or concerned: Get medical advice/attention. Rinse mouth. Remove/Take off immediately all contaminated clothing. Wash contaminated clothing before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Merck
14,2790
Beilstein
1096207
Hazard Class
6.1
Packing Group
III
Harmonized Tariff Code
2934.99
TSCA
No
RTECS
RO0205000

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