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Cytochalasin B is used for characterizing some of the polymerization properties of actin, and in studies on cytokinesis. Probe for the two hexose-transport systems in rat L6 myoblasts. And induces DNA fragmentation, inhibits cell division, and disrupts many cell processes. Inhibits glucose transport.
Susan MacLean-Fletcher.; Thomas D. Pollard. Mechanism of action of cytochalasin B on actin. Cell. 1998 , 20, (2), 329-341.
Michael Fenech.; Alexander A. Morley. Measurement of micronuclei in lymphocytes. Mutation Research/Environmental Mutagenesis and Related Subjects. 1985, 147, (1-2), 29-36.
Hazard Statements: H300-H310-H330-H361
Fatal if swallowed. Fatal in contact with skin. Fatal if inhaled. Suspected of damaging fertility or the unborn child.
Precautionary Statements: P201-P202-P260-P262-P264b-P270-P271-P281-P284-P301+P310-P302+P350-P304+P340-P308+P313-P310-P330-P361-P363-P501c
Obtain special instructions before use. Do not handle until all safety precautions have been read and understood. Do not breathe dust/fume/gas/mist/vapours/spray. Do not get in eyes, on skin, or on clothing. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Use only outdoors or in a well-ventilated area. Use personal protective equipment as required. Wear respiratory protection. IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. IF ON SKIN: Gently wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF exposed or concerned: Get medical advice/attention. Rinse mouth. Remove/Take off immediately all contaminated clothing. Wash contaminated clothing before reuse. Dispose of contents/ container to an approved waste disposal plant