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418805-02-4 - Ubiquitin E1 Inhibitor, PYR-41 - Ubiquitin-Activating Enzyme E1 Inhibitor - PYR-41 - J65388 - Alfa Aesar

J65388 Ubiquitin E1 Inhibitor, PYR-41

CAS Number
418805-02-4
Synonyms
Ubiquitin-Activating Enzyme E1 Inhibitor
PYR-41

Size Price ($) Quantity Availability
25mg 206.00
100mg 600.00
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Ubiquitin E1 Inhibitor, PYR-41

MDL
MFCD01469983

Chemical Properties

Formula
C17H13N3O7•3H2O
Formula Weight
425.40
Form
Solid
Sensitivity
Light Sensitive
Solubility
Soluble in DMSO at 5mg/ml with warming

Applications

PYR 41 is an irreversible and cell-permeable UBE1 inhibitor.

Notes

Light sensitive. Store in cool, dry place in a tightly sealed container. Store away from oxidizing agents, heat, light. Store in refrigerator.

Literature References

A G Eldridge and T O'Brien. Therapeutic strategies within the ubiquitin proteasome system. Cell Death and Differentiation. 2010, 17, 4-13.

Dana Ungermannova; 1Seth J. Parker; Christopher G. Nasveschuk; Douglas A. Chapnick; Andrew J. Phillips; Robert D. Kuchta Xuedong Liu. Identification and Mechanistic Studies of a Novel Ubiquitin E1 Inhibitor. J Biomol Screen. 2012, 17, (4), 421-434.

GHS Hazard and Precautionary Statements

Hazard Statements: H302-H317

Harmful if swallowed. May cause an allergic skin reaction.

Precautionary Statements: P261-P280g-P301+P312a-P363-P321-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves. IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Wash contaminated clothing before reuse. Specific treatment (see label). Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Harmonized Tariff Code
2934.99
TSCA
No

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