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J65388 Ubiquitin E1 Inhibitor, PYR-41

CAS Number
418805-02-4
Synonyms
Ubiquitin-Activating Enzyme E1 Inhibitor
PYR-41

Stock No. Size Price ($) Quantity Availability
J65388-MB 25mg 192.00
J65388-MC 100mg 559.00
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Ubiquitin E1 Inhibitor, PYR-41

MDL
MFCD01469983

Chemical Properties

Formula
C17H13N3O7•3H2O
Formula Weight
425.40
Form
Solid
Storage & Sensitivity
Store at -20°C. Light Sensitive.
Solubility
Soluble in DMSO at 5mg/ml with warming

Applications

PYR 41 is an irreversible and cell-permeable UBE1 inhibitor.

Notes

Light sensitive. Store in cool, dry place in a tightly sealed container. Store away from oxidizing agents, heat, light. Store in refrigerator.

Literature References

A G Eldridge and T O'Brien. Therapeutic strategies within the ubiquitin proteasome system. Cell Death and Differentiation. 2010, 17, 4-13.

Dana Ungermannova; 1Seth J. Parker; Christopher G. Nasveschuk; Douglas A. Chapnick; Andrew J. Phillips; Robert D. Kuchta Xuedong Liu. Identification and Mechanistic Studies of a Novel Ubiquitin E1 Inhibitor. J Biomol Screen. 2012, 17, (4), 421-434.

GHS Hazard and Precautionary Statements

Hazard Statements: H302-H317

Harmful if swallowed. May cause an allergic skin reaction.

Precautionary Statements: P261-P264b-P270-P272-P280g-P301+P312-P302+P352-P330-P333+P313-P363-P501c

Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Contaminated work clothing should not be allowed out of the workplace. Wear protective gloves. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. IF ON SKIN: Wash with plenty of soap and water. Rinse mouth. If skin irritation or rash occurs: Get medical advice/attention. Wash contaminated clothing before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Harmonized Tariff Code
2934.99
TSCA
No

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