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α-Casein can be an immunogen in young children, and anti-α-casein antibodies have strong cross-reactivity with insulin. This effect can explain the uncommon insulin autoimmunity, but it does not appear to progress to Type I diabetes.
François Chevalier; Alan L Kelly. Proteomic quantification of disulfide-linked polymers in raw and heated bovine milk. Journal of Agricultural and Food Chemistry. 2010, 58, (12), 7437-7444.
K L Houseknecht; D E Bauman; D G Fox; D F Smith. Abomasal infusion of casein enhances nitrogen retention in somatotropin-treated steers. Journal of Nutrition. 1992, 122, (8), 1717-1725.