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Lipoprotein, low density, oxidized, human plasma, 99%, BT-910 - Ox-LDL - Oxidized LDL - J65591 - Alfa Aesar

J65591 Lipoprotein, low density, oxidized, human plasma, 99%, BT-910

CAS Number
Synonyms
Ox-LDL
Oxidized LDL

Size Price ($) Quantity Availability
2mg 220.42
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Lipoprotein, low density, oxidized, human plasma, 99%, BT-910

Chemical Properties

Form
Liquid

Applications

Oxidized LDL induces foam cell formation in some macrophage cell lines. Research on foam cell formation is relevant to the study of atherosclerosis. Cellular exposure to ox-LDL results is the formation of lipid droplets containing cholesteryl esters in the cytoplasm of the macrophage as the lipoprotein particles are metabolized by the cell.Lipoprotein, low density, oxidized, human plasma, is evaluated for receptor binding to peritoneal macrophages. Further, it is used to induce foam cell formation in macrophages.

Notes

Supplied at 2mg/ml in 1X phosphate-buffered saline at pH 7.4 and 0.3 mM EDTA. Contains gentamicin sulfate. Aseptically packaged and sterile filtered. Store at 4°C. Do not freeze. Short shelf life: up to 6 weeks. TBARS: 29-44 nmoles MDA/mg

Literature References

Amezaga, N.; Sanjurjo, L.; Julve, J.; Aran, G.; Perez-Cebezas, B.; Bastos-Amador, P.; Armengol, C.; Vilella, R.; Escola-Gil, J. C.; Blanco-Vaca, F.; Borras, F. E.; Valledor, A. F.; Sarrias, M. -R. Human scavenger protein AIM increases foam cell formation and CD36-mediated oxLDL uptake. J Leukoc Bio 2013, 95 (3), 509-520.

Zhang, Y.; Ye, Y.; Wang, Y.; Chen, W. Inhibition of Lectin-Like Oxidized Low-Density Lipoprotein Receptor 1 Protects against Plasma/Hypoxia-Mediated Trophoblast Dysfunction Associated with Preeclampsia. Gynecol. Obstet. Invest. 2013, 79 (2), 90-96.

Zhang, Y.; Xie, Y.; You, S.; Han, Q.; Cao, Y.; Zhang, X.; Xiao, G.; Chen, R.; Liu, C. Autophagy and Apoptosis in the Response of Human Vascular Endothelial Cells to Oxidized Low-Density Lipoprotein. Cardiology 2015, 132 (1), 27-33.

Other References

Harmonized Tariff Code
2937.19
TSCA
No

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