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**Product Being Discontinued…Please See Below**
For future orders, Thermo Fisher Scientific offers high-quality lipoprotein reagents under the Invitrogen™ and Gibco™ brands.
The available replacement can be found here: Invitrogen™ Low Density Lipoprotein from Human Plasma, DiI complex (DiI LDL)
DiI-Ac-LDL is used to label vascular endothelial cells and macrophages and isolate these cells from mixed cell populations. When cells are labeled with DiI-Ac-LDL, the lipoprotein is degraded by lysosomal enzymes and the fluorescent probe accumulates in the intracellular membranes.DiI-Lipoprotein, low density, acetylated, human plasma is used to flag both macrophages and vascular endothelial cells in order to identify and isolate these from populations of mixed cells.
Bai, C.; Hou, L.; Zhang, M.; Pu, Y.; Guan, W.; Ma, Y. Characterization of vascular endothelial progenitor cells from chicken bone marrow, BMC Vet Res 2012, 8 (54), pp 10.
Do, H. T.; Bruelle, C.; Pham, D. D.; Jauhiainen, M.; Eriksson, O.; Korhonen, L. T.; Lindholm, D. Characterization of vascular endothelial progenitor cells from chicken bone marrow. J. Neurochem. 2015, 136 (2), 306-315.
Jiang, H.; Zhang, J.; Du, Y.; Jia, X.; Yang, F.; Si, S.; Wang, L.; Hong, B. microRNA-185 modulates low density lipoprotein receptor expression as a key posttranscriptional regulator. Atherosclerosis 2015, 243 (2), 523-532.