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J65607 Cephalothin sodium salt

CAS Number
58-71-9
Synonyms
7-(2-Thienylacetamido)cephalosporanic acid sodium salt
Cephalotin sodium salt

Stock No. Size Price ($) Quantity Availability
J65607-03 1g 89.40
J65607-06 5g 315.00
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Cephalothin sodium salt

MDL
MFCD00072025
EINECS
200-394-6

Chemical Properties

Formula
C16H15N2NaO6S2
Formula Weight
418.42
Form
Powder
Storage & Sensitivity
Keep Cold.
Solubility
Soluble in water

Applications

Cephalothin sodium salt is used to study the mechanism of liposome encapsulated antibiotics1, strategies for co-opting β-lactamases of Gram-negative bacteria for treatment of antibiotics2, and for immunology studies in relation to antibiotics.3 It is used to study the effect of expression, binding and inhibition of penicillin-binding proteins especially PBP6 on bacterial cell wall mucopeptide synthesis.

Notes

Store away from strong oxidizing agents. Keep container tightly closed. Store in cool, dry conditions in well sealed containers.

Literature References

Robert R. Chauvette.; Edwin H. Flynn. Chemistry of Cephalosporin Antibiotics. V.1 Amides and Esters of Cephalothin2. J. Med. Chem. 1966, 9, (5), 741-745.

Murillo, J.A.; Lemus, J.M.; Garcia, L.F. Resolution of binary mixtures of cephalothin and clavulanic acid by using first derivative spectrophotometry. Fresenius' Journal of Analytical Chemistry. 1994, 349, (10), 761-767.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H317-H319-H334-H335

Causes skin irritation. May cause an allergic skin reaction. Causes serious eye irritation. May cause allergy or asthma symptoms or breathing difficulties if inhaled. May cause respiratory irritation.

Precautionary Statements: P261-P264b-P271-P272-P280-P285-P302+P352-P304+P340-P305+P351+P338-P333+P313-P337+P313-P342+P311-P362-P501c

Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Contaminated work clothing should not be allowed out of the workplace. Wear protective gloves/protective clothing/eye protection/face protection. In case of inadequate ventilation wear respiratory protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. If skin irritation or rash occurs: Get medical advice/attention. If eye irritation persists: If experiencing respiratory symptoms: Call a POISON CENTER or doctor/physician. Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Merck
14,1982
Beilstein
4120706
Harmonized Tariff Code
2941.90
TSCA
No
RTECS
XI0388300

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