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2'-Fluoro-2'-deoxycytidine is a potent inhibitor of the subgenomic hepatitis C virus replicon in Huh-7 cells. 2'-Fluoro-2'-deoxycytidine has been shown to inhibit Borna Disease virus replication and spread.
Michel Blandin.; Tran-Dinh Son.; Joseph C. Catlin.; Wilhelm Guschlbauer. Nucleoside conformations: 16. Nuclear magnetic resonance and circular dichroism studies on pyrimidine-2?-fluoro-2?-deoxyribonucleosides. Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis. 1974, 361, (3), 249-256.
Wohlrab, F.; Jamieson, A.T.; Hay, J.; Rolf Mengel.; Guschlbauer, W. The effect of 2?-fluoro-2?-deoxycytidine on herpes virus growth. Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 1985, 824, (3), 233-242.
Hazard Statements: H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362-P501c
Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant