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1255942-06-3 - Azadibenzocyclooctyne-amine - ADIBO-amine - J65637 - Alfa Aesar

J65637 Azadibenzocyclooctyne-amine

CAS Number
1255942-06-3
Synonyms
ADIBO-amine

Size Price ($) Quantity Availability
25mg 128.00
100mg 344.00
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Azadibenzocyclooctyne-amine

MDL
MFCD22380759

Chemical Properties

Formula
C18H16N2O
Formula Weight
276.33
Form
Solid

Applications

Azadibenzocyclooctyne amine is a carbonyl reactive reagent used to incorporate ADIBO into organic compounds, surfaces or particlesAzadibenzocyclooctyne amine is widely useful in strain-promoted copper-free azide-alkyne cycloaddition reactions. It reacts with azide functionalized compounds or bimolecules to give stable triazole linkage without a need for a Cu(I) catalyst.

Notes

Heat sensitive. Incompatible with amines and azides.

Literature References

Kuzmin, A.; Poloukhtine, A.; Wolfert, M. A.; Popik, V. V. Surface Functionalization Using Catalyst-Free Azide-Alkyne Cycloaddition. Bioconjugate Chem. 2010, 21 (11), 2076-2085.

Orski, S. V.; Sheppard, G. R.; Arumugam, S.; Arnold, R. M.; Popik, V. V.; Locklin, J. Rate Determination of Azide Click Reactions onto Alkyne Polymer Brush Scaffolds: A Comparison of Conventional and Catalyst-Free Cycloadditions for Tunable Surface Modification. Langmuir 2012, 28 (41), 14693-14702.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280a-P305+P351+P338-P304+P340-P405-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Harmonized Tariff Code
2933.99
TSCA
No

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