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DAPT is used in the study of β-amyloid formation. DAPT has been shown to inhibit Notch signaling in studies of autoimmune and lymphoproliferative diseases, such as ALPS and lupus erythematosus, as well as in cancer cell growth, angiogenesis, and differentiation of human induced pluripotent stem cells.
Qian Hua.; Ye Zhiwen.; Lv Chunxu. Ultrasonically promoted nitrolysis of DAPT to HMX in ionic liquid. Ultrasonics Sonochemistry. 2008, 15, (4), 326-329.
Jayanthi, S.; Madhu, P.K.; Ramanathan, K.V. Measurement of Carbon-Proton Dipolar Couplings in Liquid Crystals Using DAPT. J. Phys. Chem. A. 2008, 112, (44), 11159-11164.