Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

J65939 Histone Acetyltransferase Inhibitor IV, CPTH2

CAS Number
357649-93-5
Synonyms
HAT Inhibitor IV
Gcn5p Inhibitor

Stock No. Size Price ($) Quantity Availability
J65939-#0 5mg 73.70
J65939-MA 10mg 117.00
Add to Cart Bulk/Specialty Print Quote View Item

Histone Acetyltransferase Inhibitor IV, CPTH2

MDL
MFCD02307488

Chemical Properties

Formula
C14H14ClN3S
Formula Weight
291.80
Form
Solid
Storage & Sensitivity
Keep Cold. Light Sensitive.
Solubility
Soluble in DMSO

Applications

Histone acetylation plays an important role in regulating the chromatin structure and is tightly regulated by two classes of enzyme, histone acetyltransferases (HAT) and histone deacetylases (HDAC). Deregulated HAT and HDAC activity plays a role in the development of a range of cancers. Consequently, inhibitors of these enzymes have potential as anticancer agents.

Notes

Light Sensitive, store in dark. Keep the container tightly closed. Store away from oxidizing agent.

Literature References

Franco Chimenti et. al. A novel histone acetyltransferase inhibitor modulating Gcn5 network: cyclopentylidene-[4-(4'-chlorophenyl)thiazol-2-yl)hydrazone. Journal of medicinal and pharmaceutical chemistry, 2009,52(2), 530-536.

Kaveri Sidhu; Vijay Kumar. c-ETS transcription factors play an essential role in the licensing of human MCM4 origin of replication. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 1849,111319-1328.

Other References

Harmonized Tariff Code
2934.10
TSCA
No

Recommended

  • 45166

    Bronze gauze, alloy 220, 40 mesh woven from 0.25mm (0.01in) in dia wire
  • H58521

    6-Benzoyl-3-(2-thienyl)-2(1H)-quinoxalinone, 97%
  • B22044

    4-Cyano-4'-n-heptyloxybiphenyl, 99%
  • A12699

    1-Adamantanamine hydrochloride, 99%
  • H60315

    (S)-2,2'-Bis[bis(3,5-di-tert-butyl-4-methoxyphenyl)phosphino]-4,4',6,6'-tetramethoxybiphenyl, 97+%

Recently Viewed

Chemicals

Life Science

Metals & Materials

Catalysts

Analytical & Labware