Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

357649-93-5 - Histone Acetyltransferase Inhibitor IV, CPTH2 - HAT Inhibitor IV - Gcn5p Inhibitor - J65939 - Alfa Aesar

J65939 Histone Acetyltransferase Inhibitor IV, CPTH2

CAS Number
357649-93-5
Synonyms
HAT Inhibitor IV
Gcn5p Inhibitor

Size Price ($) Quantity Availability
5mg 77.10
10mg 123.00
Add to Cart Add to Quote Request View Item

Histone Acetyltransferase Inhibitor IV, CPTH2

MDL
MFCD02307488

Chemical Properties

Formula
C14H14ClN3S
Formula Weight
291.80
Form
Solid
Sensitivity
Light Sensitive
Solubility
Soluble in DMSO

Applications

Histone acetylation plays an important role in regulating the chromatin structure and is tightly regulated by two classes of enzyme, histone acetyltransferases (HAT) and histone deacetylases (HDAC). Deregulated HAT and HDAC activity plays a role in the development of a range of cancers. Consequently, inhibitors of these enzymes have potential as anticancer agents.

Notes

Light Sensitive, store in dark. Keep the container tightly closed. Store away from oxidizing agent.

Literature References

Franco Chimenti et. al. A novel histone acetyltransferase inhibitor modulating Gcn5 network: cyclopentylidene-[4-(4'-chlorophenyl)thiazol-2-yl)hydrazone. Journal of medicinal and pharmaceutical chemistry, 2009,52(2), 530-536.

Kaveri Sidhu; Vijay Kumar. c-ETS transcription factors play an essential role in the licensing of human MCM4 origin of replication. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 1849,111319-1328.

Other References

Harmonized Tariff Code
2934.10
TSCA
No

Recommended

  • A13521

    2-Aminobenzothiazole, 98%
  • 14597

    Terbium(III) oxalate decahydrate, REacton®, 99.9% (REO)
  • A10211

    Tetraethylammonium tetrafluoroborate, 99%
  • 44485

    Titanium foil, 1.6mm (0.063in) thick, annealed, 99.2% (metals basis)
  • B25554

    5-Chlorovanillin, 96%

Recently Viewed

Chemicals

Life Science

Metals & Materials

Catalysts

Analytical & Labware