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2'-Fluoro-2'-deoxyuridine is used as a component incorporated into therapeutic oligonucleotides to combat prostate and breast cancer.
Charles L. Perrin. Mechanism of hydrogen exchange in amides. J. Am. Chem. Soc. 1974, 96, (17), 5628-5631.
Osamu Shimomura; Ikuyoshi Tomita; Takeshi Endo. Cationic polymerization of glycidyl phenyl ether initiated by various arylsulfoniu~ salts as new thermal latent cationic initiators. Macromol. Rapid Cammun. 1998, 19 (9), 493-497 .
Hazard Statements: H315-H319-H335-H341
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation. Suspected of causing genetic defects.
Precautionary Statements: P201-P202-P261-P264b-P271-P280i-P281-P302+P352-P304+P340-P305+P351+P338-P308+P313-P332+P313-P337+P313-P362-P501c
Obtain special instructions before use. Do not handle until all safety precautions have been read and understood. Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear eye/face protection. Use personal protective equipment as required. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF exposed or concerned: Get medical advice/attention. If skin irritation occurs: If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant