Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

J65997 Aurora Kinase/Cdk Inhibitor

CAS Number

Stock No. Size Price ($) Quantity Availability
J65997-#0 5mg 352.00
Add to Cart Bulk/Specialty Print Quote View Item

Aurora Kinase/Cdk Inhibitor


Chemical Properties

Formula Weight
Storage & Sensitivity
Keep Cold. Light Sensitive. Store under Argon.
Soluble in DMSO at 15mg/ml


Aurora Kinase/Cdk Inhibitor is a broad spectrum inhibitor of cyclin-dependent kinases and aurora kinases including CDK1/Cyclin B, CDK2/Cyclin A, CDK2/Cyclin E, Aurora-A and Aurora-B. It as been shown to induce growth suppression and mitotic defects, these results suggest that Aurora Kinase/Cdk Inhibitor could be useful for cell cycle analysis and therapy of various cancers, including Ewing's sarcoma.


Light Sensitive, store in dark. Keep the container tightly closed. Store away from oxidizing agent. Store under dry inert gas.

Literature References

Emanuel, al. The in vitro and in vivo effects of JNJ-7706621: a dual inhibitor of cyclin-dependent kinases and aurora kinases. Cancer Res., 2005,65(19), 9038-9046.

Lin, R. et al. 1-Acyl-1H-[1,2,4]triazole-3,5-diamine analogues as novel and potent anticancer cyclin-dependent kinase inhibitors: synthesis and evaluation of biological activities. J Med Chem., 2005,48(13), 4208-11.

GHS Hazard and Precautionary Statements

Hazard Statements: H302-H315-H319-H335

Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P337+P313-P362-P501c

Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Rinse mouth. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Harmonized Tariff Code


  • H61342

    Methyl 3-(2-bromophenyl)propionate, 98%
  • H32331

    2,3,5-Trifluorobenzenesulfonyl chloride, 97%
  • H25924

    2,4-Dimethyl-6-nitroaniline, 97%
  • H25777

    (S)-(+)-N,N-Dimethyl-1-ferrocenylethylamine (L)-tartrate, 95%
  • L18060

    2-Cyclohexylbenzoic acid, 97%

Recently Viewed


Life Science

Metals & Materials


Analytical & Labware