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10417-94-4 - cis-5,8,11,14,17-Eicosapentaenoic acid - EPA - Timnodonic acid - J66060 - Alfa Aesar

J66060 cis-5,8,11,14,17-Eicosapentaenoic acid

CAS Number
10417-94-4
Synonyms
EPA
Timnodonic acid

Size Price ($) Quantity Availability
100mg 191.00
500mg 370.00
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cis-5,8,11,14,17-Eicosapentaenoic acid

MDL
MFCD00065716

Chemical Properties

Formula
C20H30O2
Formula Weight
302.45
Form
Oil
Melting point
-54°
Flash Point
93°(199°F)
Density
0.943
Refractive Index
1.4975
Sensitivity
Air & Light Sensitive
Solubility
Soluble in methanol

Applications

Important polyunsaturated fatty acid of the marine food chain that serves as a precursor for the prostaglandin-3 and thromboxane-3 families. It differs from arachidonic acid (the eicosatetraenoic acid that is a precursor for the prostaglandin and thromboxane-2 families) by the extra double bond between the third and fourth carbons from the “methyl end” of the molecule. Antilipemic.

Notes

Air and Light Sensitive, store in dark and away form light. Keep container tightly closed in a dry and well-ventilated place. Store away from oxidizing agent.

Literature References

Wada, M., DeLong, C.J., Hong, Y.H., et al. Enzymes and receptors of prostaglandin pathways with arachidonic acid-derived versus eicosapentaenoic acid-derived substrates and products. J Biol Chem, 2007,282(31), 22254-22266.

Yerram, N.R.; Moore, S.A.; and Spector, A.A. Eicosapentaenoic acid metabolism in brain microvessel endothelium: Effect on prostaglandin formation. Lipid Res, 1989,301747-1757.

GHS Hazard and Precautionary Statements

Hazard Statements: H227-H314-H318

Combustible liquid. Causes severe skin burns and eye damage. Causes serious eye damage.

Precautionary Statements: P210u-P260u-P303+P361+P353-P305+P351+P338-P405-P501a

IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Beilstein
1714433
Hazard Class
8
Packing Group
III
Harmonized Tariff Code
2916.19
TSCA
No

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