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56391-57-2 - Netilmicin sulfate, 595 µg/mg - 1-N-Ethylsisomicin - J66302 - Alfa Aesar

J66302 Netilmicin sulfate, 595 µg/mg

CAS Number
56391-57-2
Synonyms
1-N-Ethylsisomicin

Size Price ($) Quantity Availability
10mg 165.00
25mg 327.00
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Netilmicin sulfate, 595 µg/mg

MDL
MFCD01311715
EINECS
260-147-3

Chemical Properties

Formula
C21H41N5O7•2.5H2SO4
Formula Weight
720.75
Form
Powder
Boiling Point
868°
Sensitivity
Light Sensitive & Hygroscopic
Solubility
Soluble in water

Applications

Netilmicin sulfate is used as a broad spectrum antibiotic active against most Gram-negative and some Gram-positive bacteria. It is a semisynthetic 1-N-ethyl derivative of sisomycin, an aminoglycoside antibiotic with action similar to gentamicin, but has less ear and kidney toxicity. It is used in aminoglycoside resistance studied

Notes

Research Use only: Not intended for animal or human diagnostic or therapeutic use.

Literature References

William A. Craig.; Sigurdur Gudmundsson.; Richard M. Reich . Netilmicin Sulfate: A Comparative Evaluation of Antimicrobial Activity, Pharmacokinetics, Adverse Reactions and Clinical Efficacy. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy. 1983, 3, (6), 305-314.

Adams, E.; Puelings, D.; Rafiee, M.; Roets, E.; Hoogmartens, J. Determination of netilmicin sulfate by liquid chromatography with pulsed electrochemical detection. Journal of Chromatography A. 1998, 812, (1-2), 151-157.

GHS Hazard and Precautionary Statements

Hazard Statements: H360-H312-H332

May damage fertility or the unborn child. Harmful in contact with skin. Harmful if inhaled.

Precautionary Statements: P201-P261-P280-P281-P304+P340-P312-P363-P308+P313-P405-P501a

Obtain special instructions before use. Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. Use personal protective equipment as required. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Call a POISON CENTER or doctor/physician if you feel unwell. Wash contaminated clothing before reuse. IF exposed or concerned: Get medical advice/attention. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,6479
Harmonized Tariff Code
2941.90
TSCA
No
RTECS
WK2286000

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