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12650-69-0 - Mupirocin, 92% - J66347 - Alfa Aesar

J66347 Mupirocin, 92%

CAS Number
12650-69-0
Synonyms

Size Price ($) Quantity Availability
50mg 285.00
100mg 456.00
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Mupirocin, 92%

MDL
MFCD01711620

Chemical Properties

Formula
C26H44O9
Formula Weight
500.62
Form
Powder
Melting point
77-78°
Boiling Point
672°
Flash Point
>110°(230°F)
Solubility
Soluble in DMSO or methanol. Sparingly soluble in water

Applications

Mupirocin is involved in inhibition of protein synthesis was reversed by isoleucine and Pseudomonic Acid was shown to inhibit IleRS (isoleucyl-tRNA synthetase) in vitro. It also demonstrates weak inhibitory action on FARSL (phenylalanyl-tRNA synthetase). Efficacy against staphylococci and streptococci including multiply resistant Staphylcoccus aureus and Staphylococcus epidermidis is reported with Pseudomonic Acid.

Notes

Research Use only: Not intended for animal or human diagnostic or therapeutic use.

Typical working concentrations are in the range of 0.25µg/mL-0.39µg/mL.

Literature References

Andrew E Simor; Tammy L Stuart; Lisa Louie; Christine Watt; Marianne Ofner-Agostini; Denise Gravel; Michael Mulvey; Mark Loeb; Allison McGeer; Elizabeth Bryce; Anne Matlow. Mupirocin-resistant, methicillin-resistant Staphylococcus aureus strains in Canadian hospitals. Antimicrobial Agents and Chemotherapy. 2007, 51, (11), 3880-3886.

Gaston H.M. Vondenhoff; Arthur Van Aerschot. Aminoacyl-tRNA synthetase inhibitors as potential antibiotics. European Journal of Medicinal Chemistry. 2011, 46, (11), 5227-5236.

GHS Hazard and Precautionary Statements

Hazard Statements: H303

May be harmful if swallowed.

Precautionary Statements: P312a

Other References

Merck
14,6302
Harmonized Tariff Code
2941.90
TSCA
No
RTECS
RA6907000

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