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107761-42-2 - Amyloid beta (1-42), human - J66387 - Alfa Aesar

J66387 Amyloid beta (1-42), human

CAS Number
107761-42-2
Synonyms

Size Price ($) Quantity Availability
0.5mg 291.00
1mg 436.00
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Amyloid beta (1-42), human

MDL
MFCD00163049

Chemical Properties

Formula
C203H311N55O60S
Formula Weight
4514.03
Form
Solid
Solubility
Soluble in ammonium hydroxide, pH >9. Also soluble in DMSO.

Applications

Aβ(s) peptides, their peptide fragments and mutated fragments are used to study a wide range of metabolic and regulatory functions including activation of kinases, regulation of cholesterol transport, function as a transcription factor, and regulators of inflammation. Aβ(s) peptides and their peptide fragments are also used to study oxidative stress, metal binding and mechanisms of protein cross-linking in the context of diseases such as Alzheimer’s disease and neurodegeneration.

Notes

Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala

Literature References

Christopher D. Syme.; John H. Viles. Solution 1H NMR investigation of Zn2+ and Cd2+ binding to amyloid-beta peptide (Aβ) of Alzheimer's disease. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics. 2006, 1764, (2), 246-256.

Elena Maltseva.; Gerald Brezesinsk. Adsorption of Amyloid Beta (1-40) Peptide to Phosphatidylethanolamine Monolayers. ChemPhysChem. 2004, 5, (8), 1185-1190.

Other References

Harmonized Tariff Code
2937.19
TSCA
No

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