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61825-94-3 - Oxaliplatin - NSC 266046 - J66586 - Alfa Aesar

J66586 Oxaliplatin

CAS Number
61825-94-3
Synonyms
NSC 266046

Size Price ($) Quantity Availability
50mg 153.47
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Oxaliplatin

MDL
MFCD00866327

Chemical Properties

Formula
C8H14N2O4Pt
Formula Weight
397.29
Form
Crystalline solid
Solubility
Soluble in water with heating and/or sonication

Applications

Oxaliplatin is an anti-tumor agent with activity against colorectal cancer. It shows antitumor activity in cell lines with acquired cisplatin resistance. It is used to treat cancer of the gullet (oesophagus). It is used as adjuvant therapy in patients who have had surgery to remove the cancer. It is used to treat testicular cancer.

Notes

Incompatible with heat and oxidizing agents.

Literature References

D Khayat; M Gil-Delgado; E C Antoine; D Nizri; G Bastian. The role of irinotecan and oxaliplatin in the treatment of advanced colorectal cancer. Oncology (Williston Park, N.Y.).2001, 15, (4), 414-415.

Peter Draxler; Silke Doris Honsek; Liesbeth Forsthuber; Viktoria Hadschieff; Jürgen Sandkühler. VGluT3? primary afferents play distinct roles in mechanical and cold hypersensitivity depending on pain etiology. Journal of Neuroscience.2014, 34, (36), 12015-12028.

GHS Hazard and Precautionary Statements

Hazard Statements: H334-H315-H319-H317-H335

May cause allergy or asthma symptoms or breathing difficulties if inhaled. Causes skin irritation. Causes serious eye irritation. May cause an allergic skin reaction. May cause respiratory irritation.

Precautionary Statements: P285-P261-P280-P305+P351+P338-P304+P340-P342+P311-P362-P312-P405-P501a

In case of inadequate ventilation wear respiratory protection. Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. If experiencing respiratory symptoms: Call a POISON CENTER or doctor/physician. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Harmonized Tariff Code
2843.90
TSCA
No
RTECS
TP2275850

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