5Z-7-oxozeaenol acts as an irreversible ATP-competitive inhibitor of ERK2 (IC<sub>50</sub> = 80 nM). It also inhibits TAK1 (MEKK7), MKK7, and MEK1, which all contain a common cysteine residue in the ATP-binding site. 5Z-7-oxozeaenol does not inhibit other MAP kinases.
Hazard Statements: H301
Toxic if swallowed.
Precautionary Statements: P264b-P270-P301+P310-P330-P501c
Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. Rinse mouth. Dispose of contents/ container to an approved waste disposal plant