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117772-70-0 - Azithromycin dihydrate - N-Methyl-11-aza-10-deoxo-10-dihydroerythromycin A - CP-62993 - J66740 - Alfa Aesar

J66740 Azithromycin dihydrate

CAS Number
117772-70-0
Synonyms
N-Methyl-11-aza-10-deoxo-10-dihydroerythromycin A
CP-62993

Size Price ($) Quantity Availability
5g 273.00
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Azithromycin dihydrate

MDL
MFCD01862248

Chemical Properties

Formula
C38H72N2O12•2H2O
Formula Weight
785.01
Form
Powder
Melting point
126°
Boiling Point
717°
Flash Point
>110°(230°F)
Sensitivity
Air Sensitive
Solubility
Soluble in DMSO at 20mg/ml. Also soluble in chloroform or ethylene chloride

Applications

Azithromycin dihydrate has anti-immunomodulatory/anti-inflammatory properties, which make it useful in treating cystic fibrosis. It shows an azalide antimicrobial agent active in vitro against various pathogens.

Notes

Research Use only: Not intended for animal or human diagnostic or therapeutic use.

Literature References

Keiko Yamauchi; Yoko Shibata; Tomomi Kimura; Shuichi Abe; Sumito Inoue; Daisuke Osaka; Michiko Sato; Akira Igarashi; Isao Kubota. Azithromycin suppresses interleukin-12p40 expression in lipopolysaccharide and interferon-gamma stimulated macrophages. International Journal of Biological Sciences.2009, 5, (7), 667-678.

Arnon Elizur; Carolyn L Cannon; Thomas W Ferkol. Airway inflammation in cystic fibrosis. Chest.2008, 133, (2), 489-495.

Other References

Harmonized Tariff Code
2941.50
TSCA
No
RTECS
RN6960000

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