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128446-36-6 - Methyl-beta-cyclodextrin - J66847 - Alfa Aesar

J66847 Methyl-beta-cyclodextrin

CAS Number
128446-36-6
Synonyms

Size Price ($) Quantity Availability
5g 37.90
25g 140.00
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Methyl-beta-cyclodextrin

MDL
MFCD00074980
EINECS
411-120-1

Chemical Properties

Form
Powder
Melting point
180-182°
Solubility
Soluble in water

Applications

Cavity size is the major determinant as to which cyclodextrin is used in complexation. The cavity diameter of β-cyclodextrins or β-glucopyranose unit compounds is well-suited for use with molecules the size of hormones, vitamins and many compounds frequently used in tissue and cell culture applications. For this reason, β-cyclodextrin is most commonly used as a complexing agent. It is used to increase the solubility of non-polar substances such as fatty acids, lipids, vitamins and cholesterol for use in cell culture applications. Methyl-β-cyclodextrin is used to remove cholesterol from cultured cells and is employed to remove lipid rafts.

Notes

Store at room temperature. Incompatible with heat, oxidizing agents.

Literature References

Yannis Dotsikas.; Yannis L Loukas. Kinetic degradation study of insulin complexed with methyl-beta cyclodextrin. Confirmation of complexation with electrospray mass spectrometry and 1H NMR. J. Pharm. Biomed. Anal. 2002, 29 (3),487-494 .

Other References

Harmonized Tariff Code
2940.00
TSCA
Yes

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    (2-Hydroxypropyl)-beta-cyclodextrin, MW ca 1250-1480

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