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J66893 N,N'-Bis(acryloyl)cystamine, Electrophoresis Reagent, 98%

CAS Number
60984-57-8
Synonyms
BAC

Stock No. Size Price ($) Quantity Availability
J66893-03 1g 51.50
J66893-06 5g 187.00
J66893-14 25g 772.00
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N,N'-Bis(acryloyl)cystamine, Electrophoresis Reagent, 98%

MDL
MFCD00036225
EINECS
262-546-8

Chemical Properties

Formula
C10H16N2O2S2
Formula Weight
260.37
Form
Powder, Packaged under argon
Melting point
123-124°
Storage & Sensitivity
Store at -20°C. Store under Nitrogen.
Solubility
Soluble at 50 mg/ml in acetic acid

Applications

BAC is used as a reversible cross-linker for polyacrylamide gels, to simplify isolation of macromolecules separated on the gels. The disulfide linkage can be broken with a suitable reducing agent. A 1-g slice of a 4% (12:1) gel will dissolve in 5 mL of 100 mM DTT in TBE (pH 8.3) in less than 30 min. The pH of 8.3 is optimum for rapid dissolution of the gel.

Notes

Store at -20°C. Incompatible with heat, oxidizing agents.

Literature References

Haruyuki Hiratani.; Carmen Alvarez-Lorenzo.; Jeffrey Chuang.; Orhan Guney.; Alexander Yu. Grosberg.; Toyoichi Tanaka. Effect of Reversible Cross-linker, N,N‘-Bis(acryloyl)cystamine, on Calcium Ion Adsorption by Imprinted Gels.Langmuir. 2001, 17 (14), 4431-4436 .

Hua Yu.; David W. Grainger. Amphiphilic Thermosensitive N-Isopropylacrylamide Terpolymer Hydrogels Prepared by Micellar Polymerization in Aqueous Media.Macromolecules . 1994, 27 (16),4554-4560 .

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362-P501c

Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Harmonized Tariff Code
2930.90
TSCA
No

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