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100986-85-4 - Levofloxacin, 98% - J66943 - Alfa Aesar

J66943 Levofloxacin, 98%

CAS Number
100986-85-4
Synonyms

Size Price ($) Quantity Availability
1g 15.90
5g 37.90
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Levofloxacin, 98%

MDL
MFCD00865049

Chemical Properties

Formula
C18H20FN3O4
Formula Weight
361.37
Form
Powder
Melting point
218-227°
Boiling Point
572°
Flash Point
>110°(230°F)
Sensitivity
Light Sensitive
Solubility
Slightly soluble in water or methanol. Soluble in glacial acetic acid or dichloromethane

Applications

Levofloxacin is a broad-spectrum antibiotic used in pharmacokinetic , antibiotic resistance , and resistance prevention studies. Levofloxacin is active against Gram-positive and Gram-negative bacteria. It inhibits DNA gyrase (type II topoisomerase) and topoisomerase IV, thereby inhibiting cell division.

Notes

Research Use only: Not intended for animal or human diagnostic or therapeutic use.

Literature References

Douglas N. Fish.; Andrew T. Chow. The Clinical Pharmacokinetics of Levofloxacin. Clinical Pharmacokinetics. 1997, 32 (2),101-119 .

Richard Frothingham M.D. Rates of Torsades de Pointes Associated with Ciprofloxacin, Ofloxacin, Levofloxacin, Gatifloxacin, and Moxifloxacin. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy. 2001, 21 (12),1468-1472 .

GHS Hazard and Precautionary Statements

Hazard Statements: H302-H334-H317

Harmful if swallowed. May cause allergy or asthma symptoms or breathing difficulties if inhaled. May cause an allergic skin reaction.

Precautionary Statements: P284-P261-P280g-P342+P311a-P301+P312a-P501a

Wear respiratory protection. Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves. If experiencing respiratory symptoms: IF SWALLOWED: Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,6771
Beilstein
7327015
Harmonized Tariff Code
2941.90
TSCA
No
RTECS
UU8815550

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