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J66943 Levofloxacin, 98%

CAS Number
100986-85-4
Synonyms

Stock No. Size Price ($) Quantity Availability
J66943-03 1g 17.10
J66943-06 5g 39.90
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Levofloxacin, 98%

MDL
MFCD00865049

Chemical Properties

Formula
C18H20FN3O4
Formula Weight
361.37
Form
Powder
Melting point
218-227°
Boiling Point
572°
Flash Point
>110°(230°F)
Storage & Sensitivity
Keep Cold. Light Sensitive.
Solubility
Slightly soluble in water or methanol. Soluble in glacial acetic acid or dichloromethane

Applications

Levofloxacin is a broad-spectrum antibiotic used in pharmacokinetic , antibiotic resistance , and resistance prevention studies. Levofloxacin is active against Gram-positive and Gram-negative bacteria. It inhibits DNA gyrase (type II topoisomerase) and topoisomerase IV, thereby inhibiting cell division.

Notes

Research Use only: Not intended for animal or human diagnostic or therapeutic use.

Literature References

Douglas N. Fish.; Andrew T. Chow. The Clinical Pharmacokinetics of Levofloxacin. Clinical Pharmacokinetics. 1997, 32 (2),101-119 .

Richard Frothingham M.D. Rates of Torsades de Pointes Associated with Ciprofloxacin, Ofloxacin, Levofloxacin, Gatifloxacin, and Moxifloxacin. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy. 2001, 21 (12),1468-1472 .

GHS Hazard and Precautionary Statements

Hazard Statements: H302-H317-H334

Harmful if swallowed. May cause an allergic skin reaction. May cause allergy or asthma symptoms or breathing difficulties if inhaled.

Precautionary Statements: P261-P264b-P270-P272-P280g-P285-P301+P312-P302+P352-P304+P341-P330-P333+P313-P342+P311-P363-P501c

Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Contaminated work clothing should not be allowed out of the workplace. Wear protective gloves. In case of inadequate ventilation wear respiratory protection. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: If breathing is difficult, remove to fresh air and keep at rest in a position comfortable for breathing. Rinse mouth. If skin irritation or rash occurs: Get medical advice/attention. If experiencing respiratory symptoms: Call a POISON CENTER or doctor/physician. Wash contaminated clothing before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Merck
14,6771
Beilstein
7327015
Harmonized Tariff Code
2934.99
TSCA
No
RTECS
UU8815550

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