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It is used and studied as a vasoprotective anti-inflammatory, anti-edematous and anti-nociceptive agent.1 It may be used to study its pharmacokinetics, safety and efficacy as a chemosensitizer and modulator of NF-κ B cell signaling
Cesare R. Sirtori. Aescin: pharmacology, pharmacokinetics and therapeutic profile. Pharmacol. Res. 2001, 44 (3), 183-193 .
Ferruccio Berti.; Claudio Omini.; Daniela Longiave. The mode of action of Aescin and the release of prostaglandins. Prostaglandins. 1977, 14 (2), 241-249 .
Hazard Statements: H302+H332-H319-H335
Harmful if swallowed. Harmful if inhaled. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P261-P264b-P270-P271-P280i-P301+P312-P304+P340-P305+P351+P338-P312-P330-P337+P313-P501c
Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Use only outdoors or in a well-ventilated area. Wear eye/face protection. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Rinse mouth. If eye irritation persists: Get medical advice/attention. Dispose of contents/ container to an approved waste disposal plant