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Ertapenem has in vitro activity against gram-positive and gram-negative aerobic and anaerobic bacteria. The bactericidal activity of ertapenem results from the inhibition of cell wall synthesis and is mediated through ertapenem binding to penicillin binding proteins.
J. Michael Williams.; Karel M. J. Brands.; Renato T. Skerlj.; Ronald B. Jobson.; George Marchesini.; Karen M. Conrad.; Brenda Pipik.; Kimberly A. Savary.; Fuh-Rong Tsay.; Peter G. Houghton .; D. Richard Sidler.; Ulf-H. Dolling.; Lisa M. DiMichele.; Thomas J. Novak. Practical Synthesis of the New Carbapenem Antibiotic Ertapenem Sodium.J. Org. Chem. 2005, 70 (19),7479-7487 .
Donald G Musson.; Kimberly L Birk.; Chester J Kitchen.; Jin Zhang.; John Y.K Hsieh.; Wei Fang.; Anup K Majumdar.; John D Rogers. Assay methodology for the quantitation of unbound ertapenem, a new carbapenem antibiotic, in human plasma.J. Chromatogr. B. 2003783 (1), 1-9 .
Hazard Statements: H315-H319
Causes skin irritation. Causes serious eye irritation.
Precautionary Statements: P264b-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313-P362
Wash face, hands and any exposed skin thoroughly after handling Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse.