Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

126411-39-0 - SR-12813, 98% - Tetraethyl 2-(3,5-di-tert-butyl-4-hydroxyphenyl)ethenyl-1,1-bisphosphonate - J67136 - Alfa Aesar

J67136 SR-12813, 98%

CAS Number
126411-39-0
Synonyms
Tetraethyl 2-(3,5-di-tert-butyl-4-hydroxyphenyl)ethenyl-1,1-bisphosphonate

Size Price ($) Quantity Availability
10mg 146.26
Add to Cart Add to Quote Request View Item

SR-12813, 98%

MDL
MFCD00888473

Chemical Properties

Formula
C24H42O7P2
Formula Weight
504.54
Form
Solid
Melting point
119-121°
Solubility
Soluble in DMSO at 25mg/ml

Applications

R-12813 was used as control in pregnane X receptor (PXR) binding assay performed in HepG2 liver carcinoma cells and PXR-activation assay mediated by dehydroepiandrosterone in human hepatocytes. It decreases the biosynthesis of cholesterol by enhancing the degradation of HMG-CoA reductase. This compound is a featured product for Gene Regulation research.

Notes

Store at -4°C. Incompatible with heat, oxidizing agents.

Literature References

Theo A Berkhout.; Helen M Simon.; Brian Jackson.; John Yates.; Nigel Pearce.; Pieter H.E Groot.; Craig Bentzen.; Eric Niesor.; William D Kerns.; Keith E Suckling. SR-12813 lowers plasma cholesterol in beagle dogs by decreasing cholesterol biosynthesis.Atherosclerosis. 1997, 133 (2),203-212 .

Other References

Harmonized Tariff Code
2931.90
TSCA
No

Recommended

  • B23285

    Ethyl oxanilate, 98%
  • 36192

    Nickel antimonide, 99.5% (metals basis excluding Co), Co 0.1-1%
  • H66207

    5-Aminopyrazine-2-carboxylic acid, 95%
  • L19329

    3-(3-Aminophenyl)propionic acid, 97%
  • H66696

    (R)-(+)-1-(1-Naphthyl)ethylamine, 97%

Recently Viewed

Chemicals

Life Science

Metals & Materials

Catalysts

Analytical & Labware