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Zeocin™, 100 mg/ml in HEPES, sterile-filtered - J67140 - Alfa Aesar

J67140 Zeocin™, 100 mg/ml in HEPES, sterile-filtered

CAS Number
Synonyms

Size Price ($) Quantity Availability
1ml 40.10
5x1ml 142.00
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Zeocin™, 100 mg/ml in HEPES, sterile-filtered

MDL
MFCD28100499

Chemical Properties

Form
Liquid
Solubility
Fully miscible.

Applications

Zeocin, a popular and effective antibiotic for the selection of vectors bearing the Sh ble gene in a variety of cells types (bacteria, eukaryotic microorganisms, plant and animal cells). Resistance to Zeocin is conferred by the Sh ble gene product, which inactivates Zeocin™ by binding to the antibiotic. Sh ble is a small gene, only 370bp in size, carried in a number of InvivoGen’s vectors. Zeocin is used as a selective agent in molecular genetics experiments.

Notes

Research Use only: Not intended for animal or human diagnostic or therapeutic use. Supplied in 10mM HEPES, pH 7.5. High ionic strength or basicity inhibits the activity of zeocin. Use at pH of approx. 7.5. For selection of E. coli concentration of NaCl should not exceed 5g/L. Zeocin is a trademark of Cayla

Literature References

TA Pfeifer.; DD Hegedus.; TA Grigliatti.; DA Theilmann. Baculovirus immediate-early promoter-mediated expression of the Zeocin resistance gene for use as a dominant selectable marker in Dipteran and Lepidopteran insect cell lines. Gene. 1997, 188, (2), 183-190.

S Takeno.; E Sakuradani.; A Tomi. Transformation of oil-producing fungus, Mortierella alpina 1S-4, using Zeocin, and application to arachidonic acid production. Journal of Bioscience and Bioengineering. 2005, 100, (6), 617-622.

GHS Hazard and Precautionary Statements

Hazard Statements: H341

Suspected of causing genetic defects.

Precautionary Statements: P201-P281-P202-P308+P313-P405-P501a

Obtain special instructions before use. Use personal protective equipment as required. Do not handle until all safety precautions have been read and understood. IF exposed or concerned: Get medical advice/attention. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Harmonized Tariff Code
2941.90
TSCA
No

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