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Used for selection of ampr transformed cells and to study the role of penicillin-sensitive transpeptidases in cell wall biosynthesis. Carboxypenicillin antibiotic that inhibits bacterial cell-wall synthesis (peptidoglycan cross-linking) by inactivating transpeptidases on the inner surface of the bacterial cell membrane. Analog to ampicillin, Antimicrobial spectrum.
H Smith.; JM Dewdney.; AW Wheeler. A comparison of the amounts and the antigenicity of polymeric materials formed in aqueous solution by some β-lactam antibiotics. Immunology. 1971, 21, (3), 527-533.
C Patsch.; D Kesseler.; F Edenhofer. Genetic engineering of mammalian cells by direct delivery of FLP recombinase protein. Methods. 1971, 53, (4), 386-393.
Hazard Statements: H334-H317
May cause allergy or asthma symptoms or breathing difficulties if inhaled. May cause an allergic skin reaction.
Precautionary Statements: P284-P261-P280g-P342+P311a-P363-P501a
Wear respiratory protection. Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves. If experiencing respiratory symptoms: Wash contaminated clothing before reuse. Dispose of contents/container in accordance with local/regional/national/international regulations.