Used for selection of ampr transformed cells and to study the role of penicillin-sensitive transpeptidases in cell wall biosynthesis. Carboxypenicillin antibiotic that inhibits bacterial cell-wall synthesis (peptidoglycan cross-linking) by inactivating transpeptidases on the inner surface of the bacterial cell membrane. Analog to ampicillin, Antimicrobial spectrum.
H Smith.; JM Dewdney.; AW Wheeler. A comparison of the amounts and the antigenicity of polymeric materials formed in aqueous solution by some β-lactam antibiotics. Immunology. 1971, 21, (3), 527-533.
C Patsch.; D Kesseler.; F Edenhofer. Genetic engineering of mammalian cells by direct delivery of FLP recombinase protein. Methods. 1971, 53, (4), 386-393.
Hazard Statements: H317-H334
May cause an allergic skin reaction. May cause allergy or asthma symptoms or breathing difficulties if inhaled.
Precautionary Statements: P261-P272-P280g-P285-P302+P352-P304+P341-P333+P313-P342+P311-P363-P501c
Avoid breathing dust/fume/gas/mist/vapours/spray. Contaminated work clothing should not be allowed out of the workplace. Wear protective gloves. In case of inadequate ventilation wear respiratory protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: If breathing is difficult, remove to fresh air and keep at rest in a position comfortable for breathing. If skin irritation or rash occurs: Get medical advice/attention. If experiencing respiratory symptoms: Call a POISON CENTER or doctor/physician. Wash contaminated clothing before reuse. Dispose of contents/ container to an approved waste disposal plant