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50-76-0 - Actinomycin D, 1 mg/ml in DMSO, sterile-filtered - Dactinomycin - Actinomycin C1 - J67160 - Alfa Aesar

J67160 Actinomycin D, 1 mg/ml in DMSO, sterile-filtered

CAS Number
50-76-0
Synonyms
Dactinomycin
Actinomycin C1

Size Price ($) Quantity Availability
1ml 65.60
5x1ml 262.00
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Actinomycin D, 1 mg/ml in DMSO, sterile-filtered

MDL
MFCD00005033
EINECS
200-063-6

Chemical Properties

Form
Liquid
Solubility
Soluble in acetonitrilie or acetone at 10 mg/mL and in DMSO at a minimum of 1 mg/mL, slightly soluble in water.

Applications

Actinomycin D has a wide-ranging applications ranging from a selection agent in cell culture, use in studies of suppressing HIV-replication and programmed cell death of PC12 cells, and as an antibiotic in treatment of various malignant neoplasms, including Wilm?s tumor and the sarcomas.

Notes

Research Use only: Not intended for animal or human diagnostic or therapeutic use.

Literature References

Perry, R.P. Selective effects of actinomycin D on the intracellular distribution of RNA synthesis in tissue culture cells.Experimental Cell Research. 1963, 29, (3), 400-406.

Paul R. Gross.; Gilles H. Cousineau. Effects of actinomycin D on macromolecule synthesis and early development in sea urchin eggs.Biochemical and Biophysical Research Communications. 1963, 10, (4), 321-326.

GHS Hazard and Precautionary Statements

Hazard Statements: H227

Combustible liquid.

Precautionary Statements: P210u-P280a-P370+P378a-P403+P235-P501a

Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Wear protective gloves and eye/face protection. In case of fire: Use for extinction: CO2, powder or water spray. Store in a well-ventilated place. Keep cool. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Harmonized Tariff Code
2941.90
TSCA
No
RTECS
AU1575000

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