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389-08-2 - Nalidixic acid, 50 mg/ml in water, sterile-filtered - J67194 - Alfa Aesar

J67194 Nalidixic acid, 50 mg/ml in water, sterile-filtered

CAS Number
389-08-2
Synonyms

Size Price ($) Quantity Availability
1ml 36.00
5x1ml 117.00
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Nalidixic acid, 50 mg/ml in water, sterile-filtered

MDL
MFCD00006884
EINECS
206-864-7

Chemical Properties

Form
Liquid
Solubility
Soluble in chloroform (50 mg/ml), ethanol (0.9 mg/ml) at 23°C, methanol (1.3 mg/ml) at 23°C, toluene (1.6 mg/ml) at 23°C, DMSO (? 6 mg/ml), and solution of carbonates. Fully miscible in water.

Applications

Nalidixic acid is an inhibitor of bacterial DNA polymerase (DNA gyrase) and avian myeloblastoma virus reverse transcriptase. It is used to modulate (inhibit) bacterial DNA gyrase-dependent processes such as DNA polymerization, (ATP-dependent)t DNA supercoiling, and chromosome fragmentation.

Notes

Research Use only: Not intended for animal or human diagnostic or therapeutic use.

Literature References

Martin Gellert.; Kiyoshi Mizuuchi.; Mary H. O'Dea.; Tateo Itoh.; Jun-Ichi Tomizawa. Nalidixic acid resistance: A second genetic character involved in DNA gyrase activity.pnas. 1977, 74 (11), 4772-4776 .

Other References

Harmonized Tariff Code
2933.99
TSCA
No
RTECS
QN2885000

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