Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

25316-40-9 - Doxorubicin hydrochloride, 10 mg/ml in DMSO, sterile filtered - J67209 - Alfa Aesar

J67209 Doxorubicin hydrochloride, 10 mg/ml in DMSO, sterile filtered

CAS Number
25316-40-9
Synonyms

SDS Certificate of Analysis Technical Inquiry
Size Price ($) Quantity Availability
1ml 252.00
Add to Cart Add to Quote Request View Item

Doxorubicin hydrochloride, 10 mg/ml in DMSO, sterile filtered

MDL
MFCD00077757
EINECS
246-818-3

Chemical Properties

Form
Liquid
Solubility
Soluble in water (50 mM), methanol, isotonic sodium chloride, and DMSO (>10 mg/ml). Insoluble in chloroform, and ether.

Applications

Doxorubicin hydrochloride is a DNA intercalator and powerful cytotoxic agent. Doxorubicin inhibits topoisomerase II which results in an increased and stabilized cleavable enzyme-DNA linked complex during DNA replication and subsequently prevents the ligation of the nucleotide strand after double-strand breakage.

Notes
Research Use only: Not intended for animal or human diagnostic or therapeutic use.

Literature References

Xiaoying Yang.; Xiaoyan Zhang.; Zunfeng Liu.; Yanfeng Ma.; Yi Huang.; Yongsheng Chen.High-Efficiency Loading and Controlled Release of Doxorubicin Hydrochloride on Graphene Oxide. J. Phys. Chem. C. 2008, 112 (45),17554-17558 .

Xiuling Xu.; Xuesi Chen.; Ping’an Ma.; Xinri Wang.; Xiabin Jing. The release behavior of doxorubicin hydrochloride from medicated fibers prepared by emulsion-electrospinning.European Journal of Pharmaceutics and Biopharmaceutics. 2008, 70 (1),165-170 .

GHS Hazard and Precautionary Statements

Hazard Statements: H350

May cause cancer.

Precautionary Statements: P201-P280-P202-P308+P313-P405-P501a

Obtain special instructions before use. Wear protective gloves/protective clothing/eye protection/face protection. Do not handle until all safety precautions have been read and understood. IF exposed or concerned: Get medical advice/attention. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Harmonized Tariff Code
2941.90
TSCA
No
RTECS
QI9295900

Recommended

  • 39223
    Hafnium telluride, 99.5% (metals basis)

  • 10231
    Magnesium rod, 3.3cm (1.3in) dia x 30cm (12in) long, 99.8% (metals basis)

  • 43298
    Magnesium slug, 6.35mm (0.25in) dia x 6.35mm (0.25in) length, 99.95% (metals basis)

  • H53177
    4-(3-Hydroxypropylcarbamoyl)benzeneboronic acid, 97%

  • 44940
    Tetramethylammonium hydroxide, 2.38% w/w aq. soln., Electronic Grade, 99.9999% (metals basis)

Recently Viewed

Chemicals

Life Science

Metals & Materials

Catalysts

Analytical & Labware