Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

75621-03-3 - CHAPS, Electrophoresis Grade - 3-[(3-Cholamidopropyl)dimethylammonio]-1-propanesulfonate - J67359 - Alfa Aesar

J67359 CHAPS, Electrophoresis Grade

CAS Number
75621-03-3
Synonyms
3-[(3-Cholamidopropyl)dimethylammonio]-1-propanesulfonate

Size Price ($) Quantity Availability
5g 110.00
10g 177.00
25g 420.00
Add to Cart Add to Quote Request View Item

CHAPS, Electrophoresis Grade

MDL
MFCD00012116

Chemical Properties

Formula
C32H58N2O7S
Formula Weight
614.88
Form
Powder
Melting point
156-158°
Sensitivity
Hygroscopic
Solubility
Soluble in water (10 mg/ml). Soluble in DMF and hot methanol.

Applications

CHAPS is often used as a detergent in the solubilization and purification of membrane proteins for several advantageous reasons. CHAPS detergent is non-denaturing to membrane proteins, can solubilize proteins, disaggregate protein-protein interactions. CHAPS is also useful in ion exchange chromatography and isoelectric focusing as it is zwitterionic and does not exhibit a net charge between pH 2 to 12. It is suitable for isolation of membrane proteins with the following features such as sufficient protein solubilization capability, no denaturing or inactivation of proteins, no interference with protein activities, no precipitation at 4°C, appropriate critical micelle concentrations (CMC) and micelle size, no absorption in the UV region, no toxicity and availability of detergent detection methods.

Notes

Hygroscopic. Store away from water/moisture and oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition. Store under inert gas.

Literature References

Jacob Anglister, et. al. Isotope-edited multidimensional NMR of calcineurin B in the presence of the non-deuterated detergent CHAPS.J. Biomol. NMR.,1993,3(1), 121-126.

F. Anne Stephenson and Richard W. Olsen. Solubilization by CHAPS Detergent of Barbiturate-Enhanced Benzodiazepine-GABA Receptor Complex.J. Neurochem.,1982,39(6), 1579-1586.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280a-P305+P351+P338-P304+P340-P405-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Harmonized Tariff Code
2924.29
TSCA
No

Recommended

  • H33079

    2-Methyl-4-(trifluoromethoxy)cinnamic acid, 97%
  • B25320

    1-Chloro-6,6-dimethyl-2-hepten-4-yne, cis + trans, tech. 90%
  • B23960

    2-(Bromoacetyl)naphthalene, 98%
  • A18197

    2,4-Dibromomesitylene, 98%
  • H64370

    5-Bromo-3-chloro-2-hydroxypyridine, 97%

Recently Viewed

Chemicals

Life Science

Metals & Materials

Catalysts

Analytical & Labware