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Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation. Required for normal branching morphogenesis. May play a role in wound healing.
Avner Yayon.; Michael Klagsbrun.; Jeffrey D. Esko.; Philip Leder.; David M. Ornitz. Cell surface, heparin-like molecules are required for binding of basic fibroblast growth factor to its high affinity receptor. Cell. 1991, 64 (4), 841-848.
W H Burgess.; T Maciag. The Heparin-Binding (Fibroblast) Growth Factor Family of Proteins. Annual Review of Biochemistry. 1989, 58 575-602.