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9041-93-4 - Bleomycin sulfate, Cell Culture Grade - J67560 - Alfa Aesar

J67560 Bleomycin sulfate, Cell Culture Grade

CAS Number
9041-93-4
Synonyms

Size Price ($) Quantity Availability
15mg 612.85
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Bleomycin sulfate, Cell Culture Grade

MDL
MFCD00070310
EINECS
232-925-2

Chemical Properties

Form
Powder
Solubility
Soluble in water or DMSO

Applications

Bleomycin sulfate binds to DNA, and can inhibit DNA synthesis and causes scission of DNA. Cleaves DNA, requires binding to oxygen and a metal ion, such as copper or iron. Able to cleave RNA, but at less and more selective degree. Also reported to induce and regulate apoptosis in a variety of cells, and inhibit tumor angiogenesis.

Notes

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: -20°C.

Literature References

Walter B. Shelley, MD, PhD.; E. Dorinda Shelley, MD. Intralesional Bleomycin Sulfate Therapy for Warts A Novel Bifurcated Needle Puncture Technique. Arch Dermatol. 1991, 127 (2), 234-236.

R.J. Sollitto, DPM, FACFAS; David M. Pizzano, DPM. Bleomycin sulfate in the treatment of mosaic plantar verrucae: A follow-up study. The Journal of Foot and Ankle Surgery. 2010, 35 (2), 169-172.

GHS Hazard and Precautionary Statements

Hazard Statements: H340-H351

May cause genetic defects. Suspected of causing cancer.

Precautionary Statements: P201-P281-P202-P308+P313-P405-P501a

Obtain special instructions before use. Use personal protective equipment as required. Do not handle until all safety precautions have been read and understood. IF exposed or concerned: Get medical advice/attention. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,1318
Harmonized Tariff Code
2941.90
TSCA
No
RTECS
EC5991990

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