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J67560 Bleomycin sulfate, Cell Culture Grade

CAS Number
9041-93-4
Synonyms

Stock No. Size Price ($) Quantity Availability
J67560-S$ 15mg 595.00
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Bleomycin sulfate, Cell Culture Grade

MDL
MFCD00070310
EINECS
232-925-2

Chemical Properties

Form
Powder
Storage & Sensitivity
Ambient temperatures.
Solubility
Soluble in water or DMSO

Applications

Bleomycin sulfate binds to DNA, and can inhibit DNA synthesis and causes scission of DNA. Cleaves DNA, requires binding to oxygen and a metal ion, such as copper or iron. Able to cleave RNA, but at less and more selective degree. Also reported to induce and regulate apoptosis in a variety of cells, and inhibit tumor angiogenesis.

Notes

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: -20°C.

Literature References

Walter B. Shelley, MD, PhD.; E. Dorinda Shelley, MD. Intralesional Bleomycin Sulfate Therapy for Warts A Novel Bifurcated Needle Puncture Technique. Arch Dermatol. 1991, 127 (2), 234-236.

R.J. Sollitto, DPM, FACFAS; David M. Pizzano, DPM. Bleomycin sulfate in the treatment of mosaic plantar verrucae: A follow-up study. The Journal of Foot and Ankle Surgery. 2010, 35 (2), 169-172.

GHS Hazard and Precautionary Statements

Hazard Statements: H340-H351-H361d

May cause genetic defects. Suspected of causing cancer. Suspected of damaging the unborn child.

Precautionary Statements: P201-P202-P281-P308+P313-P501c

Obtain special instructions before use. Do not handle until all safety precautions have been read and understood. Use personal protective equipment as required. IF exposed or concerned: Get medical advice/attention. Dispose of contents/ container to an approved waste disposal plant

Other References

Merck
14,1318
Harmonized Tariff Code
2941.90
TSCA
No
RTECS
EC5991990

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