Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

Anionic Acid Labile Surfactant I (AALS I), Certified Mass Spec Grade - J67647 - Alfa Aesar

J67647 Anionic Acid Labile Surfactant I (AALS I), Certified Mass Spec Grade

At neutral pH, Anionic Acid Labile Surfactant I acts as a detergent for use in sample preparation, protein solubilization, and cell lysis protocols. It is an alternative to SDS and other commonly used anionic detergents for protein analysis. When experimental solutions are adjusted to a pH of 2.5 - 3 with trifluoroacetic acid (TFA) and incubated for 10 minutes, the acid labile surfactant is fully cleaved into small organic molecules that do not exhibit surfactant activity or interfere with mass spectrometry analysis. The detergent is compatible with ESI and MALDI mass spectrometry analysis.

CAS Number

Size Price ($) Quantity Availability
5mg 240.00
Add to Cart Add to Quote Request View Item

Anionic Acid Labile Surfactant I (AALS I), Certified Mass Spec Grade

Chemical Properties

Lyophilized Powder


This detergent is effective at solubilizing peptides and proteins, optimizing enzymatic digestions, and reducing surface adsorption losses via non-specific interactions


Exhibits fast degradation kinetics at acidic pH's between 2.0 to 3.0. The critical micellular concentration (CMC) is 7.7mM.

Other References

Harmonized Tariff Code


  • 36736

    Sodium metaborate tetrahydrate, tech.
  • A14639

    2,4-Difluorobenzenesulfonyl chloride, 98%
  • H31679

    3-[3-Chloro-5-(trifluoromethoxy)phenyl]propionic acid, 94%
  • H50923

  • H32305

    Agarose beads 4% B-CL (Cross-linked)

Recently Viewed


Life Science

Metals & Materials


Analytical & Labware