L00137 1-Acetylimidazole, 98%
SDS
| Size | Price ($) | Quantity | Availability |
|---|---|---|---|
| 5g | 17.00 |
|
|
| 25g | 33.20 |
|
|
| 100g | 89.30 |
|
|
1-Acetylimidazole, 98%
Chemical Properties
Applications
It is a mild acylating agent and its reactivity can be enhanced by quaternization with, e.g. benzyl bromide. 1-Acetylimidazole was used as acetylation reagent for amino groups. It was also employed for acetylation of histones. It is relatively specific reagent for tyrosyl residue acetylatioa dn a reagent used in the synthesis of annulated imidazole derivatives.
Notes
Literature References
Feucht W, et al. Variation of the nuclear, subnuclear and chromosomal flavanol deposition in hemlock and rye.Int. J. Mol. Sci.,2007,8,(7), 635-50.
Marburg S and Jencks WP. The Solvolysis of 1-Acetylimidazole in Concentrated Acid and Salt Solutions.J. Am. Chem. Soc.,1962,84,(2), 232-39.
Mild acylating agent. Reactivity can be enhanced by quaternization with, e.g. benzyl bromide: Chem. Pharm. Bull., 30, 4242 (1982). Acylation of nitromethane salts leads to acylnitro compounds: Synthesis, 478 (1978).
