Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

L00286 3-Chloroperoxybenzoic acid, 50-55%, cont. ca 10% 3-chlorobenzoic acid, balance water

CAS Number
m-Chloroperbenzoic acid

Stock No. Size Price ($) Quantity Availability
L00286-14 25g 31.70
L00286-22 100g 91.40
L00286-36 500g 261.00
Add to Cart Bulk/Specialty Print Quote View Item

3-Chloroperoxybenzoic acid, 50-55%, cont. ca 10% 3-chlorobenzoic acid, balance water


Chemical Properties

Formula Weight
Melting point
Storage & Sensitivity
Keep Cold.
Soluble in potassium hydroxide, chloroform and acetone. Insoluble in water.


3-Chloroperoxybenzoic acid is a strong oxidizing agent used in the oxidation reactions such as aldehydes and ketones to esters (Bayer-Villiger-Oxidation), olefines to epoxides, sulfides to sulfoxides and sulfones, and amines to nitroalkanes, N-oxides.


Heat sensitive. Incompatible with reactive with reducing agents, combustible materials, organic materials and alkalies.

Literature References

Reagent for epoxidation of alkenes: J. Org. Chem., 29, 1976 (1964). Dichloromethane has been recommended as solvent for these reactions, since the peracid is soluble, but the by-product, 3-chlorobenzoic acid, is almost insoluble. For high-yield, stereospecific epoxidation in a two-phase, almost neutral system, see: J. Org. Chem., 44, 1351 (1979). For regioselective epoxidation of the more substituted double bond of a diene, see: Org. Synth. Coll., 5, 467 (1973). For epoxidation in aqueous solution followed by in situ hydrolysis to the trans-diol by 10% sulfuric acid, see: Synth. Commun., 19, 1939 (1989).

Carbonyl compounds undergo the Baeyer-Villiger reaction to give esters or lactones: J. Org. Chem., 29, 2914 (1964). For an extensive review of the Baeyer-Villiger reaction, see: Org. React., 43, 251 (1993).

Primary aliphatic amines are oxidized to nitro-compounds: J. Org. Chem., 31, 524 (1966). Good yields are obtained in 1,2-dichloroethane solution: J. Org. Chem., 44, 659 (1979); 54, 2869 (1989).

Sulfides can be oxidized selectively either to sulfoxides or sulfones: Tetrahedron, 22, 1235 (1966); J. Chem. Soc. (C), 2720 (1969); J. Org. Chem., 35, 2106 (1970).

For the stereospecific oxidation of imines to oxaziridines under phase-transfer conditions, see: Org. Synth. Coll., 8, 546 (1993):

Perfluorooxaziridines have been prepared using acetonitrile as solvent: J. Org. Chem., 58, 4754 (1993).

For a brief feature on uses of this reagent in Organic synthesis, see: Synlett, 664 (2007).

WARNING: The reagent has been reported to react exothermically with DMF: Org. Process Res. Dev., 6, 159 (2004).

Ernould, B.; Devos, M.; Bourgeois, J.; Rolland, J.; Vlad, A.; Gohy, J. Grafting of a redox polymer onto carbon nanotubes for high capacity battery materials. J. Mater. Chem. A 2015, 3 (16), 8832-8839.

Giuliano, M. W.; Lin, C.; Romney, D. K.; Miller, S. J.; Anslyn, E. V. A Synergistic Combinatorial and Chiroptical Study of Peptide Catalysts for Asymmetric Baeyer-Villiger Oxidation. Ind. Eng. Chem. Res. 2015, 357 (10), 2301-2309.

GHS Hazard and Precautionary Statements

Hazard Statements: H242-H302-H314-H317-H335

Heating may cause a fire. Harmful if swallowed. Causes severe skin burns and eye damage. May cause an allergic skin reaction. May cause respiratory irritation.

Precautionary Statements: P210-P220-P234-P260-P264b-P270-P271-P272-P280-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P333+P313-P363-P501c

Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Keep/Store away from clothing/combustible materials. Keep only in original container. Do not breathe dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Use only outdoors or in a well-ventilated area. Contaminated work clothing should not be allowed out of the workplace. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician. Rinse mouth. Do NOT induce vomiting. If skin irritation or rash occurs: Get medical advice/attention. Wash contaminated clothing before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Hazard Class
Packing Group
Harmonized Tariff Code


  • A11766

    Allyl bromide, 99%, stab. with 300-1000ppm Propylene oxide
  • A12646

    Triethylamine, 99%
  • A13064

    tert-Butyldimethylchlorosilane, 97%
  • 13431

    Sodium hydride, 57-63% oil dispersion
  • 89892

    Oxone®, monopersulfate

Recently Viewed


Life Science

Metals & Materials


Analytical & Labware