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It is used as a GC reagent for detection of sterols at low concentration as flophemesyl derivatives, readily detected by electron capture. Chlorodimethyl(pentafluorophenyl)silane is an extremely sensitive derivatizing agent for the analysis of sterols and lower aliphatic alcohols by electron capture gas chromatography.
Ainsley J. Francis, et al. Flophemesyl derivatives of alcohols, phenols, amines and carboxylic acids and their use in gas chromatography with electron-capture detection.J. Chromatogr. A.,1978,1,(21), 111-117.
E.D. Morgan, et al. Formation of pentafluorophenyldimethylsilylethers and their use in the gas chromatographic analysis of sterols.J. Chromatogr. A.,1975,104(2), 351-358.
GC reagent for detection of sterols at low concentration as flophemesyl derivatives, readily detected by electron capture: J. Chromat., 89, 225 (1974); 104, 351 (1975); 161, 111 (1978); Org. Mass Spectrom., 11, 671 (1978).
Hazard Statements: H314-H318
Causes severe skin burns and eye damage. Causes serious eye damage.
Precautionary Statements: P260u-P303+P361+P353-P305+P351+P338-P301+P330+P331-P405-P501a
IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.