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L00720 Bromopyruvic acid, 97%

CAS Number
1113-59-3
Synonyms
3-Bromo-2-oxopropionic acid

Stock No. Size Price ($) Quantity Availability
L00720-04 2g 30.00
L00720-09 10g 75.90
L00720-18 50g 288.00
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Bromopyruvic acid, 97%

MDL
MFCD00002587
EINECS
214-206-5

Chemical Properties

Formula
C3H3BrO3
Formula Weight
166.96
Melting point
75-80°
Storage & Sensitivity
Keep Cold.
Solubility
Soluble in water, dimethyl sulfoxide, ethyl acetate and water.

Applications

Bromopyruvic acid is used as an affinity label for cysteine residues and a potential anti-cancer agent. It is involved in the synthesis of imidazo[1,2-a]pyridine-2-carboxylic acids and substituted pyranones. It plays a vital role as a cross-linker between nucleic acids and proteins. It is used as an anticancer agent for lung tumors.

Notes

Moisture and air sensitive. Store in cool place. Incompatible with strong oxidizing agents and reducing agents.

Literature References

Cruz, O. H.; Zolotukhin, M. G.; Fomine, S.; Alexandrova, L.; Lugo, C. A.; Trevino, F. A. R.; Ortiz, G. R.; Maldonado, J. L.; Pliego, G. C. High-Tg Functional Aromatic Polymers. macromolecules 2015, 48 (4), 1026-1037.

Pietkiewicz, A. L.; Wahyudi, H.; McConnell, J. R.; McAlpine, S. R. Synthesis of macrocycles that inhibit protein synthesis: stereochemistry and structural based studies on sanguinamide B derivatives. Tetrahedron Lett. 2014, 55 (51), 6979-6982.

GHS Hazard and Precautionary Statements

Hazard Statements: H314-H335

Causes severe skin burns and eye damage. May cause respiratory irritation.

Precautionary Statements: P260-P264b-P271-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P501c

Do not breathe dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician. Wash contaminated clothing before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Beilstein
1746786
Hazard Class
8
Packing Group
II
Harmonized Tariff Code
2918.30
TSCA
Yes
RTECS
UZ0840000

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