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1113-59-3 - Bromopyruvic acid, 97% - 3-Bromo-2-oxopropionic acid - L00720 - Alfa Aesar

L00720 Bromopyruvic acid, 97%

CAS Number
1113-59-3
Synonyms
3-Bromo-2-oxopropionic acid

Size Price ($) Quantity Availability
2g 28.80
10g 72.30
50g 275.00
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Bromopyruvic acid, 97%

MDL
MFCD00002587
EINECS
214-206-5

Chemical Properties

Formula
C3H3BrO3
Formula Weight
166.96
Melting point
75-80°
Solubility
Soluble in water, dimethyl sulfoxide, ethyl acetate and water.

Applications

Bromopyruvic acid is used as an affinity label for cysteine residues and a potential anti-cancer agent. It is involved in the synthesis of imidazo[1,2-a]pyridine-2-carboxylic acids and substituted pyranones. It plays a vital role as a cross-linker between nucleic acids and proteins. It is used as an anticancer agent for lung tumors.

Notes

Moisture and air sensitive. Store in cool place. Incompatible with strong oxidizing agents and reducing agents.

Literature References

Cruz, O. H.; Zolotukhin, M. G.; Fomine, S.; Alexandrova, L.; Lugo, C. A.; Trevino, F. A. R.; Ortiz, G. R.; Maldonado, J. L.; Pliego, G. C. High-Tg Functional Aromatic Polymers. macromolecules 2015, 48 (4), 1026-1037.

Pietkiewicz, A. L.; Wahyudi, H.; McConnell, J. R.; McAlpine, S. R. Synthesis of macrocycles that inhibit protein synthesis: stereochemistry and structural based studies on sanguinamide B derivatives. Tetrahedron Lett. 2014, 55 (51), 6979-6982.

GHS Hazard and Precautionary Statements

Hazard Statements: H314-H318

Causes severe skin burns and eye damage. Causes serious eye damage.

Precautionary Statements: P280-P303+P361+P353-P305+P351+P338-P310

Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician.

Other References

Beilstein
1746786
Hazard Class
8
Packing Group
II
Harmonized Tariff Code
2918.30
TSCA
Yes
RTECS
UZ0840000

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