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2-Chloro-3,5-dinitropyridine is used as efficient pie electron acceptor in the preparation of charge transfer complexes with aniline and its derivatives acting as donors.
Ali Reza Harifi-Mood.; Aziz Habibi-Yangjeh.; Mohammad Reza Gholami. Solvent effects on kinetics of the reaction between 2-chloro-3,5-dinitropyridine and aniline in aqueous and alcoholic solutions of [bmim]BF4. International Journal of Chemical Kinetics. 2007, 39, (12), 681-687.
Dick A. De Bie.; Bart Geurtsen.; Henk C. Van der Plas. On the amination of halonitropyridines. J. Org. Chem. 1985, 50, (4), 484-487.
Reagent for the N-protection of amino acids. Derivatives are stable to acid but cleaved by ammonia: Gazz. Chim. Ital., 93, 65 (1963); 94, 616 (1964); Eur. J. Biochem., 7, 328 (1968). See Appendix 6.
In pyridine solution, functions as a condensing agent in the formation of esters from acids and alcohols: Bull. Chem. Soc. Jpn., 56, 639 (1983).
Hazard Statements: H300-H315-H319-H335
Fatal if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P261-P280a-P301+P310a-P305+P351+P338-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF SWALLOWED: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.