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1121-89-7 - Glutarimide, 98% - Piperidine-2,6-dione - L00968 - Alfa Aesar

L00968 Glutarimide, 98%

CAS Number
1121-89-7
Synonyms
Piperidine-2,6-dione

Size Price ($) Quantity Availability
5g 44.91
25g 101.70
100g 256.50
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Glutarimide, 98%

MDL
MFCD00006670
EINECS
214-340-4

Chemical Properties

Formula
C5H7NO2
Formula Weight
113.12
Melting point
153-157°
Solubility
Soluble in water, hot ethanol and boiling benzene. Insoluble in ether.

Applications

Glutarimide acts as an inhibitor of protein synthesis. Further, it is used as a reactant for thionations and biocatalytic asymmetric synthesis of sitagliptin production. It is also employed in the generation of beta-adrenoceptor ligands, enantioselective synthesis of securinega alkaloids and alfa-fluoro-alfa amino amides. In addition to this, it is used in intramolecular amidocyclopropanation reactions.

Notes

Incompatible with strong oxidizing agents.

Literature References

Sundaram, S.; Heine, D.; Hertweck, C. Polyketide synthase chimeras reveal key role of ketosynthase domain in chain branching. Nat. Chem. Biol. 2015, 11, 949-951.

Kortüm, K. M.; Zhu, Y. X.; Shi, C. X.; Jedlowski, P.; Stewart, A. K. Cereblon binding molecules in multiple myeloma. Blood Rev. 2015, 29 (5), 329-334.

Other References

Beilstein
110052
Harmonized Tariff Code
2925.19
TSCA
No
RTECS
MA4000000

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