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20120-21-2 - Ethyl 3-dimethylaminopropionate, 97% - 3-Dimethylaminopropionic acid ethyl ester - L01542 - Alfa Aesar

L01542 Ethyl 3-dimethylaminopropionate, 97%

CAS Number
20120-21-2
Synonyms
3-Dimethylaminopropionic acid ethyl ester

Size Price ($) Quantity Availability
25g 90.20
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Ethyl 3-dimethylaminopropionate, 97%

MDL
MFCD00015166
EINECS
243-524-7

Chemical Properties

Formula
(CH3)2NCH2CH2CO2CH2CH3
Formula Weight
145.20
Boiling Point
56-57°/12mm
Flash Point
58°(136°F)
Density
0.915
Refractive Index
1.4190
Solubility
Immiscible with water.

Applications

Ethyl 3-dimethylaminopropionate is used in the preparation of [3-(dimethylamino)propionyl]guanidine.

Notes

Incompatible with oxidizing agents.

Literature References

Alkyl 3-dimethylaminopropionates have been used as the synthetic equivalents of acrylate anions, by ɑ-lithiation, reaction with the appropriate electrophile and elimination: J. Org. Chem., 46, 4536 (1981):

Vanderveen, J. R.; Durelle, J.; Jessop, P. G. Design and evaluation of switchable-hydrophilicity solvents. Green Chem. 2014, 16, 1187-1197.

Zhi, Y.; Gao, L. X.; Jin, Y.; Tang, C. L.; Li, J. Y.; Li, J.; Long, Y. Q. 4-Quinolone-3-carboxylic acids as cell-permeable inhibitors of protein tyrosine phosphatase 1B. Bioorg. Med. Chem. 2014, 22 (14), 3670-3683.

GHS Hazard and Precautionary Statements

Hazard Statements: H226-H315-H319-H335

Flammable liquid and vapour. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P280g-P305+P351+P338

Wear protective gloves. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Other References

Beilstein
1702477
Hazard Class
3
Packing Group
III
Harmonized Tariff Code
2922.49
TSCA
No
RTECS
AY5992700

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