Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

5467-74-3 - 4-Bromobenzeneboronic acid, 97+% - 4-Bromophenylboronic acid - L01565 - Alfa Aesar

L01565 4-Bromobenzeneboronic acid, 97+%

CAS Number
5467-74-3
Synonyms
4-Bromophenylboronic acid

Size Price ($) Quantity Availability
1g 19.50
5g 72.70
25g 300.00
Add to Cart Add to Quote Request View Item

4-Bromobenzeneboronic acid, 97+%

MDL
MFCD00002104
EINECS
226-779-9

Chemical Properties

Formula
C6H6BBrO2
Formula Weight
200.83
Melting point
282-286°
Solubility
Soluble in methanol. Insoluble in water.

Applications

4-Bromobenzeneboronic acid is a reagent used for Palladium catalyzed Suzuki-Miyaura cross-couplings, Tandem-type Pd(II)-catalyzed oxidative Heck reaction and intramolecular C-H amidation sequence. It is also used in the preparation of Protein modulators and enzymatic and kinase inhibitors, Gallate-based obovatol analogs with potential anti-tumor activity. It is used as a reagent for Copper-mediated ligandless aerobic fluoroalkylation of arylboronic acids with fluoroalkyl iodides, Pd-catalyzed arylative cyclization of alkyne-tethered enals or enones via carbopalladation of alkynes, Copper-catalyzed cross-couplings.

Notes

Store in a cool and dark place. Store away from incompatible materials such as oxidizing agents. Incompatible with Oxidizing agents, Acids, Bases, Alcohols

Literature References

GC reagent for diols: J. Chromat., 158, 33 (1978); 186, 307 (1979).

Carbonylative cross-coupling with iodobenzenes and CO, catalyzed by trans-Dichlorobis(triphenyl­phosphine)­palladium(II)­, 10491, gives unsymmetrical diaryl ketones: Tetrahedron Lett., 34, 7595 (1993); J. Org. Chem., 63, 4726 (1998). For reactions of boronic acids, see Appendix 5.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280a-P305+P351+P338-P304+P340-P405-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Beilstein
2936347
Harmonized Tariff Code
2931.90
TSCA
No
RTECS
CY8650000

Recommended

Recently Viewed

Chemicals

Life Science

Metals & Materials

Catalysts

Analytical & Labware