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Nicotinic hydrazide is used in hydrazone library formation. It is used to study the oxidation of isonicotinic acid hydrazide (ionized) by horseradish peroxidase. Nicotinic hydrazide is an inhibitor of peroxidase enzyme. It forms solid metal complexes having strong biological activity
Kai Johnsson.; Peter G. Schultz. Mechanistic Studies of the Oxidation of Isoniazid by the Catalase Peroxidase from Mycobacterium tuberculosis. J. Am. Chem. Soc. 1994, 116, (16), 7425-7426.
M.M.Abou Sekkina.; M.G.Abou El-Azm. Thermo-chemical behavior of solid nicotinic hydrazide metal complexes in correlation with their stoichiometry. Thermochimica Acta. 1984, 77, (1-3), 211-218.
Hazard Statements: H351
Suspected of causing cancer.
Precautionary Statements: P201-P280-P202-P308+P313-P405-P501a
Obtain special instructions before use. Wear protective gloves/protective clothing/eye protection/face protection. Do not handle until all safety precautions have been read and understood. IF exposed or concerned: Get medical advice/attention. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.