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526-55-6 - Tryptophol, 97% - 3-(2-Hydroxyethyl)indole - 2-(3-Indolyl)ethanol - L02555 - Alfa Aesar

L02555 Tryptophol, 97%

CAS Number
526-55-6
Synonyms
3-(2-Hydroxyethyl)indole
2-(3-Indolyl)ethanol

Size Price ($) Quantity Availability
1g 21.87
5g 69.01
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Tryptophol, 97%

MDL
MFCD00005659
EINECS
208-393-2

Chemical Properties

Formula
C10H11NO
Formula Weight
161.20
Melting point
56-59°
Boiling Point
174°/2mm
Flash Point
255°(491°F)
Solubility
Solubility in methanol gives very faint turbidity. Soluble in water at 25°C 2749 mg/L.

Applications

It is employed as a reactant for preparation of inhibitors of the C-terminal domain of RNA polymerase II and their antitumor activities, anti-HIV-1 agents, inhibitors of Protein-Protein Interactions, partial agonists of the serotonin 5-HT1A receptor, growth hormone secretagogues, vascular endothelial growth factor (VEGF) inhibitors, A2B adenosine receptor ligands, potential detoxification inhibitors of the crucifer phytoalexin brassinin, inhibitors of interleukin and dual binding site acetyl cholinesterase inhibitors.

Notes

Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.

Literature References

Cesarini, S, et al. (Hetero)aroyl esters of 2-(N-phthalimido)ethanol and analogs: Parallel synthesis, anti-HIV-1 activity and cytotoxicity.Med. Chem. Res.,2010,19(311).

Alex Shaginian, et. al. Design, synthesis, and evaluation of an alpha-helix mimetic library targeting protein-protein interactions.J Am Chem. Soc.,2009,131(15), 5564-5572.

Other References

Merck
14,9798
Beilstein
125553
Harmonized Tariff Code
2933.79
TSCA
Yes
RTECS
KL3685000

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